ENSMUSG00000020821


Mus musculus

Features
Gene ID: ENSMUSG00000020821
  
Biological name :Kif1c
  
Synonyms : Kif1c / Kinesin-like protein KIF1C / O35071
  
Possible biological names infered from orthology : kinesin family member 1C / O43896
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B3
Gene start: 70700548
Gene end: 70731964
  
Corresponding Affymetrix probe sets: 10377953 (MoGene1.0st)   10377982 (MoGene1.0st)   1424746_at (Mouse Genome 430 2.0 Array)   1424747_at (Mouse Genome 430 2.0 Array)   1426325_at (Mouse Genome 430 2.0 Array)   1436224_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092075
Ensembl peptide - ENSMUSP00000123242
Ensembl peptide - ENSMUSP00000136258
Ensembl peptide - ENSMUSP00000072048
Ensembl peptide - ENSMUSP00000099614
NCBI entrez gene - 16562     See in Manteia.
MGI - MGI:1098260
RefSeq - XM_006532323
RefSeq - NM_153103
RefSeq - XM_006532320
RefSeq - XM_006532321
RefSeq - XM_006532322
RefSeq Peptide - NP_694743
swissprot - E9Q9B0
swissprot - O35071
swissprot - Q3V3Y9
Ensembl - ENSMUSG00000020821
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-375g18.1ENSDARG00000075024Danio rerio
 KIF1CENSG00000129250Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kif1a / kinesin family member 1A / Q12756*ENSMUSG0000001460253
Kif1b / Q60575 / Kinesin-like protein KIF1B / O60333* / kinesin family member 1B*ENSMUSG0000006307753
Kif13b / kinesin family member 13B / Q9NQT8*ENSMUSG0000006001234
Kif13a / kinesin family member 13A / Q9H1H9*ENSMUSG0000002137534
Q80TF6 / Stard9 / StAR-related lipid transfer protein 9 / Q9P2P6* / StAR related lipid transfer domain containing 9*ENSMUSG0000003370530
B1AVY7 / Kif16b / Kinesin-like protein KIF16B / Q96L93* / kinesin family member 16B*ENSMUSG0000003884428
Kif14 / L0N7N1 / Kinesin-like protein KIF14 / Q15058* / kinesin family member 14*ENSMUSG0000004149827
Kif28ENSMUSG0000008723624


Protein motifs (from Interpro)
Interpro ID Name
 IPR000253  Forkhead-associated (FHA) domain
 IPR001752  Kinesin motor domain
 IPR008984  SMAD/FHA domain superfamily
 IPR019821  Kinesin motor domain, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR027640  Kinesin-like protein
 IPR032405  Kinesin-associated
 IPR036961  Kinesin motor domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IDA
 biological_processGO:0007018 microtubule-based movement IBA
 biological_processGO:0030705 cytoskeleton-dependent intracellular transport IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IBA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0016887 ATPase activity IBA


Pathways (from Reactome)
Pathway description
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001875 testis inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the testis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Kif1cOrch3-DBA/2J/Kif1cOrch3-DBA/2J
Genetic Background: involves: BALB/cByJ * DBA/2

 MP:0001876 decreased inflammatory response "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Cpoxnct/Cpoxnct,Nctm2BALB/c/Nctm2BALB/c
Genetic Background: involves: BALB/c * MSM

Allelic Composition: Kif1cOrch3-DBA/2J/Kif1cOrch3-DBA/2J
Genetic Background: involves: BALB/cByJ * DBA/2

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cd9tm1Mek/Cd9tm1Mek
Genetic Background: involves: 129/Sv * C57BL/6

 MP:0002409 decreased susceptibility to infection "reduced likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Spi1tm1Sing/Spi1+,Spibtm1Mcs/Spib+
Genetic Background: involves: 129S/SvEv * 129X1/SvJ

Allelic Composition: Kif1cLtxs1-DBA/2NCr/Kif1cLtxs1-DBA/2NCr,Ltxs2DBA/2NCr/Ltxs2DBA/2NCr,Ltxs3DBA/2NCr/Ltxs3DBA/2NCr
Genetic Background: involves: BALB/cAnPt * DBA/2NCr

 MP:0002412 increased susceptibility to bacterial infection "greater likelihood that an organism will develop ill effects from a bacterial infection or from components of or toxins produced by bacteria" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Rettm1Cos/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv

Allelic Composition: Kif1cLtxs1/Kif1c+
Genetic Background: involves: C3H/HeJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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