ENSMUSG00000039318


Mus musculus

Features
Gene ID: ENSMUSG00000039318
  
Biological name :Rab3gap2
  
Synonyms : Rab3gap2 / RAB3 GTPase activating non-catalytic protein subunit 2
  
Possible biological names infered from orthology : Q9H2M9
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H5
Gene start: 185204117
Gene end: 185286759
  
Corresponding Affymetrix probe sets: 10352459 (MoGene1.0st)   1436272_at (Mouse Genome 430 2.0 Array)   1454915_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000066325
Ensembl peptide - ENSMUSP00000141608
NCBI entrez gene - 98732     See in Manteia.
MGI - MGI:1916043
RefSeq - NM_001163754
RefSeq - XM_006497216
RefSeq Peptide - NP_001157226
swissprot - E9QKE4
swissprot - A0A0A6YWM5
Ensembl - ENSMUSG00000039318
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rab3gap2ENSDARG00000044136Danio rerio
 RAB3GAP2ENSGALG00000009503Gallus gallus
 Q9H2M9ENSG00000118873Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR026059  Rab3-GAP regulatory subunit
 IPR029257  Rab3GAP regulatory subunit, C-terminal
 IPR032839  Rab3-GAP regulatory subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0097051 establishment of protein localization to endoplasmic reticulum membrane IEA
 biological_processGO:1903061 positive regulation of protein lipidation IEA
 biological_processGO:1903373 positive regulation of endoplasmic reticulum tubular network organization IEA
 biological_processGO:2000786 positive regulation of autophagosome assembly IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0017112 Rab guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA


Pathways (from Reactome)
Pathway description
COPI-independent Golgi-to-ER retrograde traffic
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000036104 Q80UJ7 / Rab3gap1 / Rab3 GTPase-activating protein catalytic subunit / Q15042* / RAB3 GTPase activating protein catalytic subunit 1*  / complex
 ENSMUSG00000015291 Gdi1 / P50396 / Rab GDP dissociation inhibitor alpha / P31150* / GDP dissociation inhibitor 1*  / reaction
 ENSMUSG00000025531 Chm / choroidermia (RAB escort protein 1) / P24386* / CHM, Rab escort protein 1*  / reaction
 ENSMUSG00000073639 Rab18 / P35293 / RAB18, member RAS oncogene family / Q9NP72*  / reaction / complex
 ENSMUSG00000078185 Chml / choroideremia-like / P26374* / CHM like, Rab escort protein 2*  / reaction
 ENSMUSG00000021218 Gdi2 / Q61598 / Rab GDP dissociation inhibitor beta / P50395* / GDP dissociation inhibitor 2*  / reaction






 

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