ENSMUSG00000041297


Mus musculus

Features
Gene ID: ENSMUSG00000041297
  
Biological name :Cdk13
  
Synonyms : Cdk13 / Cyclin-dependent kinase 13 / Q69ZA1
  
Possible biological names infered from orthology : Q14004
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A2
Gene start: 17710315
Gene end: 17805097
  
Corresponding Affymetrix probe sets: 10407892 (MoGene1.0st)   1440833_at (Mouse Genome 430 2.0 Array)   1443038_at (Mouse Genome 430 2.0 Array)   1452897_at (Mouse Genome 430 2.0 Array)   1458313_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152820
Ensembl peptide - ENSMUSP00000036013
Ensembl peptide - ENSMUSP00000152539
Ensembl peptide - ENSMUSP00000152546
NCBI entrez gene - 69562     See in Manteia.
MGI - MGI:1916812
RefSeq - XM_011244344
RefSeq - NM_001081058
RefSeq - NM_027118
RefSeq - XM_006516766
RefSeq - XM_006516767
RefSeq Peptide - NP_081394
RefSeq Peptide - NP_001074527
swissprot - A0A1Y7VNQ1
swissprot - Q69ZA1
swissprot - A0A1Y7VLM0
Ensembl - ENSMUSG00000041297
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdk13ENSDARG00000076791Danio rerio
 CDK13ENSGALG00000043243Gallus gallus
 CDK13ENSG00000065883Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cdk12 / Q14AX6 / Cyclin-dependent kinase 12 / Q9NYV4*ENSMUSG0000000311941
Cdk9 / Q99J95 / Cyclin-dependent kinase 9 / P50750*ENSMUSG000000095558


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000380 alternative mRNA splicing, via spliceosome IDA
 biological_processGO:0006368 transcription elongation from RNA polymerase II promoter IBA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030097 hemopoiesis IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0070816 phosphorylation of RNA polymerase II C-terminal domain IEA
 biological_processGO:2000737 negative regulation of stem cell differentiation IMP
 cellular_componentGO:0002945 cyclin K-CDK13 complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IBA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0008024 cyclin/CDK positive transcription elongation factor complex IBA
 cellular_componentGO:0016607 nuclear speck ISO
 cellular_componentGO:0019908 nuclear cyclin-dependent protein kinase holoenzyme complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding IBA
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IBA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019901 protein kinase binding IDA
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of DNA Repair Genes
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021258 Ccnk / cyclin K / O75909*  / complex / reaction






 

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