ENSMUSG00000042625


Mus musculus

Features
Gene ID: ENSMUSG00000042625
  
Biological name :Safb2
  
Synonyms : Q80YR5 / Safb2 / scaffold attachment factor B2
  
Possible biological names infered from orthology : Q14151
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: D
Gene start: 56560965
Gene end: 56584585
  
Corresponding Affymetrix probe sets: 10452085 (MoGene1.0st)   10452087 (MoGene1.0st)   1427987_at (Mouse Genome 430 2.0 Array)   1427988_s_at (Mouse Genome 430 2.0 Array)   1452629_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123229
Ensembl peptide - ENSMUSP00000120845
Ensembl peptide - ENSMUSP00000123673
Ensembl peptide - ENSMUSP00000074953
Ensembl peptide - ENSMUSP00000116363
Ensembl peptide - ENSMUSP00000117696
Ensembl peptide - ENSMUSP00000119141
Ensembl peptide - ENSMUSP00000119324
Ensembl peptide - ENSMUSP00000120750
NCBI entrez gene - 224902     See in Manteia.
MGI - MGI:2146808
RefSeq - XM_017317444
RefSeq - NM_001029979
RefSeq - NM_001355463
RefSeq - XM_006524156
RefSeq - XM_006524157
RefSeq - XM_006524159
RefSeq Peptide - NP_001342392
RefSeq Peptide - NP_001025150
swissprot - D6RHP9
swissprot - F6R703
swissprot - F6VRR0
swissprot - F6WIZ2
swissprot - F6XJ79
swissprot - D6RJ78
swissprot - F6Z0Y5
swissprot - Q80YR5
Ensembl - ENSMUSG00000042625
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 safbENSDARG00000020467Danio rerio
 ENSGALG00000013365Gallus gallus
 ENSGALG00000001948Gallus gallus
 SAFB2ENSG00000130254Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Safb / D3YXK2 / Scaffold attachment factor B1 / Q15424* / scaffold attachment factor B*ENSMUSG0000007105459
Sltm / Q8CH25 / SAFB-like, transcription modulator / Q9NWH9*ENSMUSG0000003221225


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR003034  SAP domain
 IPR034782  Scaffold attachment factor B2
 IPR035979  RNA-binding domain superfamily
 IPR036361  SAP domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0050684 regulation of mRNA processing IEA
 biological_processGO:0060008 Sertoli cell differentiation IMP
 biological_processGO:0060765 regulation of androgen receptor signaling pathway IMP
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002776 Sertoli cell hyperplasia "increased number of cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:71710, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Socs2tm1Vem/Socs2tm1Vem
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0004851 increased testis weight "greater average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Socs2tm1Vem/Socs2tm1Vem
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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