ENSMUSG00000042772


Mus musculus

Features
Gene ID: ENSMUSG00000042772
  
Biological name :Smg7
  
Synonyms : Protein SMG7 / Q5RJH6 / Smg7
  
Possible biological names infered from orthology : Q92540 / SMG7, nonsense mediated mRNA decay factor
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: G3
Gene start: 152836995
Gene end: 152902646
  
Corresponding Affymetrix probe sets: 10358757 (MoGene1.0st)   1455574_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041241
Ensembl peptide - ENSMUSP00000073144
Ensembl peptide - ENSMUSP00000107467
NCBI entrez gene - 226517     See in Manteia.
MGI - MGI:2682334
RefSeq - XM_017319981
RefSeq - NM_001005507
RefSeq - NM_001160256
RefSeq - NM_001160257
RefSeq - XM_006529451
RefSeq - XM_006529452
RefSeq - XM_017319978
RefSeq - XM_017319979
RefSeq - XM_006529450
RefSeq Peptide - NP_001153728
RefSeq Peptide - NP_001153729
RefSeq Peptide - NP_001005507
swissprot - Q5RJH6
Ensembl - ENSMUSG00000042772
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smg7ENSDARG00000060767Danio rerio
 SMG7ENSGALG00000004667Gallus gallus
 SMG7ENSG00000116698Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Smg6 / P61406 / Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) / Q86US8* / SMG6, nonsense mediated mRNA decay factor*ENSMUSG0000003829016
Smg5 / Q6ZPY2 / Protein SMG5 / Q9UPR3* / SMG5, nonsense mediated mRNA decay factor*ENSMUSG0000000141513


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR018834  DNA/RNA-binding domain, Est1-type
 IPR019458  Telomerase activating protein Est1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0006406 mRNA export from nucleus IBA
 biological_processGO:0007004 telomere maintenance via telomerase IBA
 biological_processGO:0043487 regulation of RNA stability IBA
 biological_processGO:0090501 RNA phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005697 telomerase holoenzyme complex IBA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0045111 intermediate filament cytoskeleton ISO
 molecular_functionGO:0004540 ribonuclease activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042162 telomeric DNA binding IBA
 molecular_functionGO:0043021 ribonucleoprotein complex binding IBA
 molecular_functionGO:0051721 protein phosphatase 2A binding ISS
 molecular_functionGO:0070034 telomerase RNA binding IBA


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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