MP:0000120 | malocclusion | "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000420 | ruffled hair | "fuzzy, irregular appearance of the hair" [J:50844] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000452 | abnormal mouth morphology | "anomalous structure or development of the oral cavity" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000572 | abnormal autopod morphology | "malformation of the hand or foot" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000599 | enlarged liver | "larger than average size of the liver" [J:65146] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0000611 | jaundice | "clinical manifestation of hyperbilirubinemia, with deposition of bile pigments in the skin, resulting in yellowish staining of the skin and mucous membranes" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0001211 | wrinkled skin | "irregular folds and/or indentations on the skin" [J:19212] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001222 | epidermal hyperplasia | "increase in size of the epidermis due to increase in epidermal cell number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0001525 | impaired balance | "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0002102 | abnormal ear morphology | "structural or developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002655 | abnormal keratinocyte morphology | "structural or developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002981 | increased liver weight | "a greater than average weight of the bile-secreting exocrine gland" [il:Ira Lu , Mouse Genome Informatics Curator] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Wwtr1tm1Hku/Wwtr1tm1Hku,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Allelic Composition: Ctgftm1.1Alea/Ctgftm1.1Alea,Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Yap1tm1c(KOMP)Mbp/Yap1tm1c(KOMP)Mbp,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * DBA
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+,Tgfbr2tm1Roes/Tgfbr2tm1Roes Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0003111 | abnormal nucleus morphology | "abnormalities in the nucleus and/or its surrounding membrane" [J:91473, smb:Susan M. Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0003158 | dysphagia | "difficulty in swallowing food or liquid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0003252 | abnormal bile duct physiology | "anomalous action or function of the channels that secrete bile from the liver to the gall bladder and intestines" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0003324 | liver adenoma | "benign epithelial neoplasm of the liver" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0003331 | hepatocellular carcinoma | "malignant neoplasm arising from liver cells" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0003333 | liver fibrosis | "invasion of fibrous connective tissue into the liver, often resulting from inflammation or injury " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Wwtr1tm1Hku/Wwtr1tm1Hku,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Allelic Composition: Ctgftm1.1Alea/Ctgftm1.1Alea,Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Yap1tm1c(KOMP)Mbp/Yap1tm1c(KOMP)Mbp,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * DBA
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+,Tgfbr2tm1Roes/Tgfbr2tm1Roes Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0003427 | parakeratosis | "abnormal retention of the nuclei of the keratinocytes in the stratum corneum of the epidermis" [smb:Susan M Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0003453 | abnormal keratinocyte physiology | "atypical function of the cells of the epidermis that produce keratin" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:94860] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0003769 | abnormal lip morphology | "anomalous structure or development of the fleshy margins of the mouth" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0003789 | osteosarcoma | "malignant neoplasm derived from bone" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003893 | increased hepatocyte proliferation | "anomalous growth and reproduction of hepatocyte cells of the liver" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0004046 | abnormal mitosis | "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0004492 | abnormal orientation of inner hair cell stereociliary bundles | "misorientation or rotation of inner hair cell (IHC) stereociliary bundles, resulting in defective planar cell polarity of the inner ear sensory epithelium" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0005344 | increased circulating bilirubin level | "greater than the normal concentration in the blood of this yellow heme breakdown product" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0008014 | lung tumor | "presence of abnormal, rapidly proliferating cells on the lung usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
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MP:0008019 | liver tumor | "presence of abnormal, rapidly proliferating cells in the liver usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
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MP:0009347 | increased cancellous bone thickness | "thicker than normal bone with a lattice-like or spongy structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0009581 | decreased keratinocyte apoptosis | "reduction in the number of keratinocytes undergoing programmed cell death" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0009583 | increased keratinocyte proliferation | "increase in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0009760 | abnormal mitotic spindle | "an anomaly in the formation of the ellipsoidal (bipolar) collection of fibers visible during nuclear division and cytokinesis responsible for accurate segregation of chromosomes during mitosis" [ISBN:8185198691 "Rieger R et al Eds Glossary of Genetics Classical and Molecular"] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0009877 | exostosis | "a projection of bone, sometimes a benign tumor, that is capped by cartilage and arises from a bone that develops from cartilage" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010293 | increased integument system tumor incidence | "greater than the expected number of tumors originating in the integument system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010297 | increased hepatobiliary system tumor incidence | |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Albtm1(cre/ERT2)Mtz/Alb+ Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
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MP:0010299 | increased mammary gland tumor incidence | "greater than the expected number of neoplasms in the mammary gland, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010300 | increased skin tumor incidence | "greater than the expected number of neoplasms in the skin tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010315 | increased cholangiocarcinoma incidence | "greater than the expected number of malignant adenocarcimomas arising in the intrahepatic bile duct epithelium, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0010318 | increased salivary gland tumor incidence | "greater than the expected number of neoplams in the salivary gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0010363 | increased fibrosarcoma incidence | "greater than the expected number of a highly aggressive malignant neoplasm arising from fibrous connective tissue, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Mcm4Sdla/Mcm4+ Genetic Background: involves: C57BL/6
Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0011095 | complete embryonic lethality between implantation and placentation | "death of all organisms of a given genotype in a population between the point of implantation and the initiation of placentation (Mus: E4.5 to less than E9)" [MGI:csmith] |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0011686 | increased epidermal stem cell number | "greater than expected number of somatic stem cells that are part of the epidermis" [CL:1000428, MGI:csmith] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Tg(KRT14-cre/ERT)20Efu/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CD-1
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MP:0012114 | absent inner cell mass proliferation | |
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Allelic Composition: Mob1atm1.2Asuz/Mob1a+,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0012236 | abnormal cholangiocyte morphology | "any structural anomaly of the epithelial cells of the bile duct that have primary cilia extending from their apical membrane into the ductal lumen; cholangiocytes are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts" [PMID:22961800] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Wwtr1tm1Hku/Wwtr1tm1Hku,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
Allelic Composition: Ctgftm1.1Alea/Ctgftm1.1Alea,Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * DBA
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Yap1tm1c(KOMP)Mbp/Yap1tm1c(KOMP)Mbp,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * DBA
Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+,Tgfbr2tm1Roes/Tgfbr2tm1Roes Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA
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MP:0013119 | abdomen swellings | "appearance of abnormal enlargements of all descriptions (hard, soft, different shapes etc) under the skin in the abdominal region" [MGI:Ahmad_Retha] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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MP:0014038 | increased hepatocyte number | "greater than normal number of parenchymal liver cells" [MGI:monikat] |
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Allelic Composition: Mob1atm1.1Asuz/Mob1atm1.1Asuz,Mob1bGt(CC0690)Wtsi/Mob1bGt(CC0690)Wtsi,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: B6.Cg-Mob1bGt(CC0690)Wtsi Mob1atm1.1Asuz Speer6-ps1Tg(Alb-cre)21Mgn
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