ENSG00000114978


Homo sapiens

Features
Gene ID: ENSG00000114978
  
Biological name :MOB1A
  
Synonyms : MOB1A / MOB kinase activator 1A / Q9H8S9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p13.1
Gene start: 74152528
Gene end: 74178898
  
Corresponding Affymetrix probe sets: 201297_s_at (Human Genome U133 Plus 2.0 Array)   201298_s_at (Human Genome U133 Plus 2.0 Array)   201299_s_at (Human Genome U133 Plus 2.0 Array)   214812_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379364
NCBI entrez gene - 55233     See in Manteia.
OMIM - 609281
RefSeq - NM_001317112
RefSeq - NM_018221
RefSeq - NM_001317110
RefSeq - NM_001317111
RefSeq Peptide - NP_001304039
RefSeq Peptide - NP_001304040
RefSeq Peptide - NP_001304041
RefSeq Peptide - NP_060691
swissprot - Q9H8S9
Ensembl - ENSG00000114978
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MOB1AENSGALG00000039203Gallus gallus
 Mob1aENSMUSG00000043131Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MOB1B / Q7L9L4 / MOB kinase activator 1BENSG0000017354294
MOB3B / Q86TA1 / MOB kinase activator 3BENSG0000012016252
MOB3A / Q96BX8 / MOB kinase activator 3AENSG0000017208151
MOB3C / Q70IA8 / MOB kinase activator 3CENSG0000014296150
MOB2 / Q70IA6 / MOB kinase activator 2ENSG0000018220839


Protein motifs (from Interpro)
Interpro ID Name
 IPR005301  MOB kinase activator family
 IPR036703  MOB kinase activator superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035329 hippo signaling TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Signaling by Hippo


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131023 LATS1 / O95835 / large tumor suppressor kinase 1  / complex / reaction
 ENSG00000101109 STK4 / Q13043 / serine/threonine kinase 4  / reaction
 ENSG00000150457 LATS2 / Q9NRM7 / large tumor suppressor kinase 2  / reaction / complex
 ENSG00000104375 STK3 / Q13188 / serine/threonine kinase 3  / reaction






 

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