ENSG00000173542


Homo sapiens

Features
Gene ID: ENSG00000173542
  
Biological name :MOB1B
  
Synonyms : MOB1B / MOB kinase activator 1B / Q7L9L4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q13.3
Gene start: 70902326
Gene end: 71022449
  
Corresponding Affymetrix probe sets: 225997_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427216
Ensembl peptide - ENSP00000310189
Ensembl peptide - ENSP00000379366
NCBI entrez gene - 92597     See in Manteia.
OMIM - 609282
RefSeq - XM_017008837
RefSeq - NM_001244766
RefSeq - NM_001244767
RefSeq - NM_173468
RefSeq - XM_005265709
RefSeq - XM_011532412
RefSeq Peptide - NP_775739
RefSeq Peptide - NP_001231695
RefSeq Peptide - NP_001231696
swissprot - Q7L9L4
swissprot - D6RCK3
Ensembl - ENSG00000173542
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mob1baENSDARG00000009169Danio rerio
 mob1bbENSDARG00000012953Danio rerio
 MOB1BENSGALG00000011573Gallus gallus
 Mob1bENSMUSG00000006262Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MOB1A / Q9H8S9 / MOB kinase activator 1AENSG0000011497892
MOB3B / Q86TA1 / MOB kinase activator 3BENSG0000012016252
MOB3A / Q96BX8 / MOB kinase activator 3AENSG0000017208151
MOB3C / Q70IA8 / MOB kinase activator 3CENSG0000014296147
MOB2 / Q70IA6 / MOB kinase activator 2ENSG0000018220838


Protein motifs (from Interpro)
Interpro ID Name
 IPR005301  MOB kinase activator family
 IPR036703  MOB kinase activator superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0031952 regulation of protein autophosphorylation IDA
 biological_processGO:0035329 hippo signaling TAS
 biological_processGO:0042327 positive regulation of phosphorylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019209 kinase activator activity IDA
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Signaling by Hippo


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000131023 LATS1 / O95835 / large tumor suppressor kinase 1  / complex / reaction
 ENSG00000150457 LATS2 / Q9NRM7 / large tumor suppressor kinase 2  / complex / reaction
 ENSG00000101109 STK4 / Q13043 / serine/threonine kinase 4  / reaction
 ENSG00000104375 STK3 / Q13188 / serine/threonine kinase 3  / reaction






 

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