ENSMUSG00000047228


Mus musculus

Features
Gene ID: ENSMUSG00000047228
  
Biological name :A2ml1
  
Synonyms : A2ml1 / alpha-2-macroglobulin like 1 / Q3UU35
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: F3
Gene start: 128539821
Gene end: 128581608
  
Corresponding Affymetrix probe sets: 10548248 (MoGene1.0st)   1436503_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000059426
NCBI entrez gene - 232400     See in Manteia.
MGI - MGI:3039594
RefSeq - NM_001001179
RefSeq Peptide - NP_001001179
swissprot - Q3UU35
Ensembl - ENSMUSG00000047228
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OVSTENSGALG00000011930Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2m / Q6GQT1 / alpha-2-macroglobulin / P01023*ENSMUSG0000003011139
Pzp / Q61838 / Pregnancy zone protein Alpha-2-macroglobulin 165 kDa subunit Alpha-2-macroglobulin 35 kDa subunitENSMUSG0000003035937
Gm7298ENSMUSG0000010802234
Mug2 / P28666 / Murinoglobulin-2 ENSMUSG0000003013134
Mug1 / P28665 / Murinoglobulin-1 ENSMUSG0000005990834
Cd109 / Q8R422 / CD109 antigen / Q6YHK3* / CD109 molecule*ENSMUSG0000004618624
C4b / P01029 / Complement C4-B Complement C4 beta chain Complement C4 alpha chain C4a anaphylatoxin Complement C4 gamma chain / C4A* / P0C0L4* / P0C0L5* / complement C4B (Chido blood group)...ENSMUSG0000007341820
C3 / P01027 / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acylation stimulating protein Complement C3b alpha chain Complement C3c alpha chain...ENSMUSG0000002416420
Hc / P06684 / hemolytic complement / C5* / P01031* / complement C5*ENSMUSG0000002687420


Protein motifs (from Interpro)
Interpro ID Name
 IPR001599  Alpha-2-macroglobulin
 IPR002890  Alpha-2-macroglobulin, N-terminal
 IPR008930  Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
 IPR009048  Alpha-macroglobulin, receptor-binding
 IPR011625  Alpha-2-macroglobulin, N-terminal 2
 IPR011626  Alpha-macroglobulin complement component
 IPR013783  Immunoglobulin-like fold
 IPR014756  Immunoglobulin E-set
 IPR019565  Alpha-2-macroglobulin, thiol-ester bond-forming
 IPR019742  Alpha-2-macroglobulin, conserved site
 IPR036595  Alpha-macroglobulin, receptor-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004866 endopeptidase inhibitor activity IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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