ENSMUSG00000047547


Mus musculus

Features
Gene ID: ENSMUSG00000047547
  
Biological name :Cltb
  
Synonyms : Clathrin light chain B / Cltb / Q6IRU5
  
Possible biological names infered from orthology : P09497
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: B1
Gene start: 54592401
Gene end: 54611344
  
Corresponding Affymetrix probe sets: 10409345 (MoGene1.0st)   1453063_at (Mouse Genome 430 2.0 Array)   1456797_at (Mouse Genome 430 2.0 Array)   1460740_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000053371
Ensembl peptide - ENSMUSP00000089198
Ensembl peptide - ENSMUSP00000122336
NCBI entrez gene - 74325     See in Manteia.
MGI - MGI:1921575
RefSeq - XM_006517418
RefSeq - NM_028870
RefSeq Peptide - NP_001334441
RefSeq Peptide - NP_083146
swissprot - Q3TWZ9
swissprot - Q6IRU5
swissprot - F7BHJ0
Ensembl - ENSMUSG00000047547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cltbENSDARG00000052368Danio rerio
 CLTBENSGALG00000003344Gallus gallus
 CLTBENSG00000175416Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Clta / clathrin light chain A / P09496*ENSMUSG0000002847857


Protein motifs (from Interpro)
Interpro ID Name
 IPR000996  Clathrin light chain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0072583 clathrin-dependent endocytosis IBA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030118 clathrin coat IEA
 cellular_componentGO:0030125 clathrin vesicle coat IBA
 cellular_componentGO:0030130 clathrin coat of trans-Golgi network vesicle IEA
 cellular_componentGO:0030132 clathrin coat of coated pit IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0060170 ciliary membrane IDA
 molecular_functionGO:0005198 structural molecule activity IBA
 molecular_functionGO:0032050 clathrin heavy chain binding IBA
 molecular_functionGO:0042277 peptide binding IEA


Pathways (from Reactome)
Pathway description
Gap junction degradation
Formation of annular gap junctions
Lysosome Vesicle Biogenesis
WNT5A-dependent internalization of FZD4
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002957 Ap2a2 / P17427 / Mus musculus adaptor-related protein complex 2, alpha 2 subunit (Ap2a2), transcript variant 1, mRNA. / O94973* / adaptor related protein complex 2 alpha 2 subunit*  / complex
 ENSMUSG00000022841 Ap2m1 / P84091 / AP-2 complex subunit mu / Q96CW1* / adaptor related protein complex 2 mu 1 subunit*  / complex
 ENSMUSG00000035152 Ap2b1 / Q9DBG3 / AP-2 complex subunit beta / P63010* / adaptor related protein complex 2 beta 1 subunit*  / complex
 ENSMUSG00000047547 Cltb / Q6IRU5 / Clathrin light chain B / P09497*  / complex
 ENSMUSG00000008036 Ap2s1 / P62743 / AP-2 complex subunit sigma / P53680* / adaptor related protein complex 2 sigma 1 subunit*  / complex
 ENSMUSG00000060279 Ap2a1 / P17426 / AP-2 complex subunit alpha-1 / O95782* / adaptor related protein complex 2 alpha 1 subunit*  / complex






 

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