ENSMUSG00000049489


Mus musculus

Features
Gene ID: ENSMUSG00000049489
  
Biological name :Fam58b
  
Synonyms : Fam58b / family with sequence similarity 58, member B / Q8QZR8
  
Possible biological names infered from orthology : CCNQ / cyclin Q / Q8N1B3
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B5
Gene start: 78750506
Gene end: 78751729
  
Corresponding Affymetrix probe sets: 10388898 (MoGene1.0st)   1451334_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050658
NCBI entrez gene - 69109     See in Manteia.
MGI - MGI:1916359
RefSeq - NM_197989
RefSeq Peptide - NP_932106
swissprot - Q8QZR8
Ensembl - ENSMUSG00000049489
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccnqENSDARG00000037537Danio rerio
 CCNQENSG00000262919Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ccnl2 / Q9JJA7 / Cyclin-L2 / Q96S94*ENSMUSG0000002906827
Ccnl1 / Q52KE7 / Mus musculus cyclin L1 (Ccnl1), transcript variant 2, mRNA. / Q9UK58* / cyclin L1*ENSMUSG0000002782926
Ccnk / cyclin K / O75909*ENSMUSG0000002125824
Ccnt2 / Q7TQK0 / Cyclin-T2 / O60583*ENSMUSG0000002634920
Ccnc / Q62447 / Cyclin-C / P24863*ENSMUSG0000002825220
Ccnt1 / Q9QWV9 / Cyclin-T1 / O60563*ENSMUSG0000001196019


Protein motifs (from Interpro)
Interpro ID Name
 IPR006671  Cyclin, N-terminal
 IPR013763  Cyclin-like
 IPR028759  Cyclin-related protein FAM58
 IPR036915  Cyclin-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032147 activation of protein kinase activity IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IGI
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IBA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 biological_processGO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity IBA
 molecular_functionGO:0030295 protein kinase activator activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1+
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Bay

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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