MP:0003733 | abnormal inner nuclear layer morphology | "malformation/anomalous structure of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
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MP:0003734 | abnormal inner plexiform layer morphology | "malformation/anomalous structure of the retinal cell layer where bipolar and amacrine cell axons synapse with ganglion cell dendrites
" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
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MP:0004021 | abnormal rod electrophysiology | "anomaly in the function of dark adapted vision mediated by the rods" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
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MP:0005018 | decreased T cell number | "fewer than normal T cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Otud7btm1(NCOM)Cmhd/Otud7btm1(NCOM)Cmhd Genetic Background: C57BL/6N-Otud7btm1(NCOM)Cmhd/Tcp
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MP:0005240 | abnormal amacrine cell morphology | "anomalous structure of the interneurons of the retina" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
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MP:0005253 | abnormal eye physiology | "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
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MP:0006069 | abnormal retinal neuronal layer morphology | "malformation in any of the neuronal layers that make up the retina, including the ganglion cell, inner plexiform, inner nuclear, outer plexiform, outer nuclear layers, the inner and outer segments" [smb:Susan M Bello, Mouse Genome Informatics Curator, Gray s Anatomy:ISBN 0-914294-08-3] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
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MP:0006073 | abnormal retinal bipolar cell morphology | "anomalous structure of the cells that transmit signals from the photoreceptors to retinal amacrine and ganglion cells" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92623:] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
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MP:0008056 | abnormal retinal ganglion cell morphology | "any structural anomaly of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
Allelic Composition: Sema5btm1.2Alk/Sema5btm1.2Alk,Tg(Thy1-EGFP)MJrs/0 Genetic Background: involves: 129 * BALB/cJ * C57BL/6 * CBA
Allelic Composition: Sema5atm1.2Alk/Sema5atm1.2Alk,Sema5btm1.2Alk/Sema5btm1.2Alk,Tg(Thy1-EGFP)MJrs/0 Genetic Background: involves: 129 * BALB/cJ * C57BL/6 * CBA
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MP:0008143 | abnormal dendrite morphology | "any structural anomaly of the highly branched tree-like process of a neuron that serves as a receptive field and conducts impulses toward the cell body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
Allelic Composition: Sema5btm1.2Alk/Sema5btm1.2Alk,Tg(Thy1-EGFP)MJrs/0 Genetic Background: involves: 129 * BALB/cJ * C57BL/6 * CBA
Allelic Composition: Sema5atm1.2Alk/Sema5atm1.2Alk,Sema5btm1.2Alk/Sema5btm1.2Alk,Tg(Thy1-EGFP)MJrs/0 Genetic Background: involves: 129 * BALB/cJ * C57BL/6 * CBA
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MP:0008415 | abnormal neurite morphology | "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572] |
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Allelic Composition: Etv6tm1.1(RUNX1,hsb5)Lvdw/Etv6+,TgTn(sb-T2/Onc)76Dla/0 Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6J * FVB/N
Allelic Composition: Sema5atm1.2Alk/Sema5atm1.2Alk,Sema5btm1.2Alk/Sema5btm1.2Alk Genetic Background: involves: 129 * BALB/cJ * C57BL/6
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MP:0009772 | abnormal retinal development | "anomaly in any of the steps during embryogenesis that produce the nerve layer lining in the back of the eye which senses light, and creates impulses that travel through the optic nerve to the brain" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Sema5atm1.2Alk/Sema5atm1.2Alk,Sema5btm1.2Alk/Sema5btm1.2Alk Genetic Background: involves: 129 * BALB/cJ * C57BL/6
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