ENSMUSG00000052688


Mus musculus

Features
Gene ID: ENSMUSG00000052688
  
Biological name :Rab7b
  
Synonyms : Q8VEA8 / Rab7b / RAB7B, member RAS oncogene family
  
Possible biological names infered from orthology : Q96AH8
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 131688695
Gene end: 131715439
  
Corresponding Affymetrix probe sets: 10349661 (MoGene1.0st)   1424987_at (Mouse Genome 430 2.0 Array)   1435830_a_at (Mouse Genome 430 2.0 Array)   1444063_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123359
Ensembl peptide - ENSMUSP00000065456
Ensembl peptide - ENSMUSP00000066452
Ensembl peptide - ENSMUSP00000116515
NCBI entrez gene - 226421     See in Manteia.
MGI - MGI:2442295
RefSeq - XM_006529433
RefSeq - NM_001311096
RefSeq - NM_145509
RefSeq - XM_006529428
RefSeq - XM_006529429
RefSeq - XM_006529430
RefSeq - XM_006529431
RefSeq Peptide - NP_001298025
RefSeq Peptide - NP_663484
swissprot - J9UUF7
swissprot - D3Z4X4
swissprot - Q8VEA8
swissprot - D3YZQ6
Ensembl - ENSMUSG00000052688
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RAB7BENSGALG00000000769Gallus gallus
 RAB7BENSG00000276600Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rab7 / P51150 / RAB7, member RAS oncogene family / RAB7A* / P51149* / RAB7A, member RAS oncogene family*ENSMUSG0000007947750
Rab9 / Q9R0M6 / RAB9, member RAS oncogene family / RAB9A* / P51151* / RAB9A, member RAS oncogene family*ENSMUSG0000007931640
Rab9b / Q8BHH2 / RAB9B, member RAS oncogene family / Q9NP90*ENSMUSG0000004346340
Rab32 / Q9CZE3 / RAB32, member RAS oncogene family / Q13637*ENSMUSG0000001983234
Rab23 / RAB23, member RAS oncogene family / Q9ULC3*ENSMUSG0000000476834
Rab38 / Q8QZZ8 / RAB38, member RAS oncogene family / P57729*ENSMUSG0000003055933
Rab29 / RAB29, member RAS oncogene family / O14966*ENSMUSG0000002643329


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032755 positive regulation of interleukin-6 production ISS
 biological_processGO:0034144 negative regulation of toll-like receptor 4 signaling pathway IMP
 biological_processGO:0034164 negative regulation of toll-like receptor 9 signaling pathway IMP
 biological_processGO:0034499 late endosome to Golgi transport ISS
 biological_processGO:0045654 positive regulation of megakaryocyte differentiation ISS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISS
 biological_processGO:0071346 cellular response to interferon-gamma IDA
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030670 phagocytic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0045335 phagocytic vesicle ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
TBC/RABGAPs
RAB geranylgeranylation
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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