ENSMUSG00000054072


Mus musculus

Features
Gene ID: ENSMUSG00000054072
  
Biological name :Iigp1
  
Synonyms : Iigp1 / Interferon-inducible GTPase 1 / Q9QZ85
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 18
Strand: 1
Band: D3
Gene start: 60376029
Gene end: 60392627
  
Corresponding Affymetrix probe sets: 10455961 (MoGene1.0st)   1419042_at (Mouse Genome 430 2.0 Array)   1419043_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032473
Ensembl peptide - ENSMUSP00000063390
NCBI entrez gene - 60440     See in Manteia.
MGI - MGI:1926259
RefSeq - XM_011246980
RefSeq - NM_001146275
RefSeq - NM_021792
RefSeq - XM_011246977
RefSeq - XM_011246978
RefSeq - XM_011246979
RefSeq Peptide - NP_001139747
RefSeq Peptide - NP_068564
swissprot - J7NNX8
swissprot - Q9QZ85
Ensembl - ENSMUSG00000054072
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 irgq2ENSDARG00000068657Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm4951ENSMUSG0000007355575
F830016B08RikENSMUSG0000009094249
Gm4841ENSMUSG0000006860647
Gm5431ENSMUSG0000005816345
9930111J21Rik1 / RIKEN cDNA 9930111J21 gene 1ENSMUSG0000006989345
Tgtp2 / Q3T9E4 / Q62293 / T-cell-specific guanine nucleotide triphosphate-binding protein 1 ENSMUSG0000007892144
Tgtp1 / Q3T9E4 / Q62293 / T-cell-specific guanine nucleotide triphosphate-binding protein 1 ENSMUSG0000007892244
Gm12185ENSMUSG0000004885244
9930111J21Rik2 / RIKEN cDNA 9930111J21 gene 2ENSMUSG0000006989243
Ifi47ENSMUSG0000007892038
Irgc1 / Mus musculus immunity-related GTPase family, cinema 1 (Irgc1), transcript variant 1, mRNA. / IRGC* / Q6NXR0* / immunity related GTPase cinema*ENSMUSG0000006202831
Irgm1 / Q60766 / Mus musculus immunity-related GTPase family M member 1 (Irgm1), transcript variant 2, mRNA. / IRGM* / A1A4Y4* / immunity related GTPase M*ENSMUSG0000004687928
Igtp / IRGM* / A1A4Y4* / immunity related GTPase M*ENSMUSG0000007885325
Irgm2 / IRGM* / A1A4Y4* / immunity related GTPase M*ENSMUSG0000006987425


Protein motifs (from Interpro)
Interpro ID Name
 IPR007743  Immunity-related GTPases-like
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR030385  IRG-type guanine nucleotide-binding (G) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0010506 regulation of autophagy IMP
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0035458 cellular response to interferon-beta IDA
 biological_processGO:0042832 defense response to protozoan IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0020005 symbiont-containing vacuole membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0032580 Golgi cisterna membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019003 GDP binding IDA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005027 increased susceptibility to parasitic infection "greater likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Esr1tm1Geog/Esr1tm1Geog
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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