ENSMUSG00000055204


Mus musculus

Features
Gene ID: ENSMUSG00000055204
  
Biological name :Ankrd17
  
Synonyms : Ankrd17 / Ankyrin repeat domain-containing protein 17 / Q99NH0
  
Possible biological names infered from orthology : ankyrin repeat domain 17 / O75179
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: E1
Gene start: 90227166
Gene end: 90366577
  
Corresponding Affymetrix probe sets: 10531215 (MoGene1.0st)   10338664 (MoGene1.0st)   10338727 (MoGene1.0st)   10338773 (MoGene1.0st)   10338779 (MoGene1.0st)   10338987 (MoGene1.0st)   10341375 (MoGene1.0st)   10341444 (MoGene1.0st)   10343039 (MoGene1.0st)   10343633 (MoGene1.0st)   10338094 (MoGene1.0st)   10340086 (MoGene1.0st)   10340711 (MoGene1.0st)   10341469 (MoGene1.0st)   10342158 (MoGene1.0st)   10342167 (MoGene1.0st)   10342321 (MoGene1.0st)   1415726_at (Mouse Genome 430 2.0 Array)   1421220_at (Mouse Genome 430 2.0 Array)   1436775_a_at (Mouse Genome 430 2.0 Array)   1445826_at (Mouse Genome 430 2.0 Array)   1454763_at (Mouse Genome 430 2.0 Array)   1459952_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151446
Ensembl peptide - ENSMUSP00000014421
Ensembl peptide - ENSMUSP00000080587
Ensembl peptide - ENSMUSP00000128960
Ensembl peptide - ENSMUSP00000142575
NCBI entrez gene - 81702     See in Manteia.
MGI - MGI:1932101
RefSeq - XM_017321182
RefSeq - NM_198010
RefSeq - XM_006535287
RefSeq - XM_006535288
RefSeq - XM_006535289
RefSeq - XM_006535290
RefSeq - XM_006535291
RefSeq - XM_011249595
RefSeq - NM_030886
RefSeq Peptide - NP_112148
RefSeq Peptide - NP_932127
swissprot - A0A1W2P6X1
swissprot - E9QKG6
swissprot - A0A0G2JDZ9
swissprot - Q99NH0
swissprot - E9Q804
Ensembl - ENSMUSG00000055204
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ANKRD17ENSGALG00000011642Gallus gallus
 O75179ENSG00000132466Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ankhd1 / ankyrin repeat and KH domain containing 1 / Q8IWZ3* / ANKHD1-EIF4EBP3* / ANKHD1-EIF4EBP3 readthrough*ENSMUSG0000002448360
Kidins220 / kinase D-interacting substrate 220 / Q9ULH0*ENSMUSG0000003633312
Tanc2 / A2A690 / Protein TANC2 / Q9HCD6* / tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2*ENSMUSG0000005358012
Tanc1 / Q0VGY8 / Protein TANC1 / Q9C0D5* / tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1*ENSMUSG0000003516811
Anks6 / Q6GQX6 / Ankyrin repeat and SAM domain-containing protein 6 / Q68DC2* / ankyrin repeat and sterile alpha motif domain containing 6*ENSMUSG000000661918
Q05921 / Rnasel / ribonuclease L (2, 5-oligoisoadenylate synthetase-dependent) / Q05823* / ribonuclease L*ENSMUSG000000668005
Ankrd29 / ankyrin repeat domain 29 / Q8N6D5*ENSMUSG000000577664
Fank1 / Q9DAM9 / Fibronectin type 3 and ankyrin repeat domains 1 protein / Q8TC84* / fibronectin type III and ankyrin repeat domains 1*ENSMUSG000000531114
Ankrd50 / ankyrin repeat domain 50ENSMUSG000000448641


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR004087  K Homology domain
 IPR004088  K Homology domain, type 1
 IPR020683  Ankyrin repeat-containing domain
 IPR036612  K Homology domain, type 1 superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001955 blood vessel maturation IMP
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006275 regulation of DNA replication IEA
 biological_processGO:0007492 endoderm development TAS
 biological_processGO:0042742 defense response to bacterium IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045087 innate immune response ISO
 biological_processGO:0045787 positive regulation of cell cycle IEA
 biological_processGO:0051151 negative regulation of smooth muscle cell differentiation IMP
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IEA
 biological_processGO:1900245 positive regulation of MDA-5 signaling pathway IEA
 biological_processGO:1900246 positive regulation of RIG-I signaling pathway IEA
 cellular_componentGO:0000785 chromatin IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000259 abnormal vascular development "malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0000267 abnormal cardiac development "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0000292 distended pericardial sacs "stretched outer parietal layer of the pericardium" [J:25248]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0000295 poorly developed ventricular trabeculae "retarded differentation of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [J:29971]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0001634 internal hemorrhage "blood loss in the interior of the body due to vessel rupture or dysmorphology " [J:23170]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0001722 pale yolk sac "bloodless yolk sac" [J:62571]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0001915 intracranial hemorrhage "bleeding within the skull, including hemorrhage into the brain and within the cranial epidural, subdural, and subarachnoid spaces" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0002151 abnormal neural tube morphology/development "anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Aph1btm1Bdes/Aph1btm1Bdes,Aph1ctm1.1Bdes/Aph1ctm1.1Bdes
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0002652 thin myocardial wall "thinly developed cardiac muscle layers" [il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0003070 increased vascular permeability "greater or faster ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0003658 abnormal capillaries "malformation in the minute blood vessels that connect arterioles and venules" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96775]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0005244 hemopericardium "bleeding into the pericardial space" [Pathology:ISBN 0-397-51047-0]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0005592 abnormal vascular smooth muscle morphology "structural anomaly of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

 MP:0011264 abnormal cardiac mesenchyme morphology "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures" [ISBN:0-683-40008-8, MGI:csmith]
Show

Allelic Composition: Atf4tm1Kry/Atf4tm1Kry,Tg(Col1a1-cre)1Kry/0
Genetic Background: involves: C57BL/6J * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr