ENSMUSG00000058056


Mus musculus

Features
Gene ID: ENSMUSG00000058056
  
Biological name :Palld
  
Synonyms : Palladin / Palld / Q9ET54
  
Possible biological names infered from orthology : palladin, cytoskeletal associated protein / Q8WX93
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: B3.1
Gene start: 61511433
Gene end: 61902690
  
Corresponding Affymetrix probe sets: 10578829 (MoGene1.0st)   1427228_at (Mouse Genome 430 2.0 Array)   1433768_at (Mouse Genome 430 2.0 Array)   1440635_at (Mouse Genome 430 2.0 Array)   1440693_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000112374
Ensembl peptide - ENSMUSP00000113874
Ensembl peptide - ENSMUSP00000119792
Ensembl peptide - ENSMUSP00000034057
Ensembl peptide - ENSMUSP00000112442
NCBI entrez gene - 72333     See in Manteia.
MGI - MGI:1919583
RefSeq - XM_011242242
RefSeq - NM_001081390
RefSeq - NM_001293772
RefSeq - NM_001293773
RefSeq - NM_001293774
RefSeq - XM_006509503
RefSeq - XM_006509504
RefSeq - XM_006509505
RefSeq - XM_006509507
RefSeq - XM_006509508
RefSeq Peptide - NP_001074859
RefSeq Peptide - NP_001280701
RefSeq Peptide - NP_001280702
RefSeq Peptide - NP_001280703
swissprot - D3Z1J5
swissprot - Q9ET54
Ensembl - ENSMUSG00000058056
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 palldENSDARG00000040009Danio rerio
 PALLDENSGALG00000009650Gallus gallus
 PALLDENSG00000129116Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mypn / Q5DTJ9 / Myopalladin / Q86TC9*ENSMUSG0000002006741
Ttn / titin / A2ASS6 / Q8WZ42*ENSMUSG0000005174727
Hmcn1 / D3YXG0 / Hemicentin-1 / Q96RW7*ENSMUSG0000006684215
Myot / Q9JIF9 / myotilin / Q9UBF9*ENSMUSG0000002447115
Hmcn2 / A2AJ76 / Hemicentin-2 / Q8NDA2*ENSMUSG0000005563214
Obscn / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF / Q5VST9*ENSMUSG0000006146213
Igsf10 / Q3V1M1 / Immunoglobulin superfamily member 10 / Q6WRI0*ENSMUSG0000003633411
Obsl1 / D3YYU8 / Obscurin-like protein 1 / O75147* / obscurin like 1*ENSMUSG000000262112


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR033017  Palladin, C-terminal immunoglobulin-like domain
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003334 keratinocyte development IMP
 biological_processGO:0003382 epithelial cell morphogenesis IMP
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0030036 actin cytoskeleton organization IMP
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0002102 podosome IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament ISS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: Galctwi/Galctwi,Ptgdrtm1Sna/Ptgdrtm1Sna
Genetic Background: B6.Cg-Galctwi Ptgdrtm1Sna

 MP:0000929 open neural tube "incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]
Show

Allelic Composition: Galctwi/Galctwi,Ptgdrtm1Sna/Ptgdrtm1Sna
Genetic Background: B6.Cg-Galctwi Ptgdrtm1Sna

 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Galctwi/Galctwi,Ptgdrtm1Sna/Ptgdrtm1Sna
Genetic Background: B6.Cg-Galctwi Ptgdrtm1Sna

 MP:0011099 complete lethality throughout fetal growth and development "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Galctwi/Galctwi,Ptgdrtm1Sna/Ptgdrtm1Sna
Genetic Background: B6.Cg-Galctwi Ptgdrtm1Sna

 MP:0011708 decreased fibroblast cell migration "reduced frequency of or less rapid cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium" [MGI:csmith]
Show

Allelic Composition: Galctwi/Galctwi,Ptgdrtm1Sna/Ptgdrtm1Sna
Genetic Background: B6.Cg-Galctwi Ptgdrtm1Sna

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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