ENSMUSG00000026211


Mus musculus

Features
Gene ID: ENSMUSG00000026211
  
Biological name :Obsl1
  
Synonyms : D3YYU8 / Obscurin-like protein 1 / Obsl1
  
Possible biological names infered from orthology : O75147 / obscurin like 1
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C4
Gene start: 75479310
Gene end: 75506452
  
Corresponding Affymetrix probe sets: 10355871 (MoGene1.0st)   1427535_s_at (Mouse Genome 430 2.0 Array)   1436414_at (Mouse Genome 430 2.0 Array)   1443510_at (Mouse Genome 430 2.0 Array)   1443801_at (Mouse Genome 430 2.0 Array)   1457121_at (Mouse Genome 430 2.0 Array)   1460414_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109197
Ensembl peptide - ENSMUSP00000117420
Ensembl peptide - ENSMUSP00000114553
Ensembl peptide - ENSMUSP00000109195
NCBI entrez gene - 98733     See in Manteia.
MGI - MGI:2138628
RefSeq - XM_006496583
RefSeq - XM_017313059
RefSeq - XM_017313058
RefSeq - XM_006496585
RefSeq - NM_001310679
RefSeq - NM_178884
RefSeq Peptide - NP_001297608
RefSeq Peptide - NP_849215
swissprot - D3YYU8
swissprot - A0A0A0MQG1
swissprot - F7AGE9
swissprot - A0A0B4J1L4
Ensembl - ENSMUSG00000026211
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 obsl1aENSDARG00000003684Danio rerio
 obsl1bENSDARG00000077388Danio rerio
 OBSL1ENSGALG00000011242Gallus gallus
 OBSL1ENSG00000124006Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Obscn / obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF / Q5VST9*ENSMUSG0000006146233
Ttn / titin / A2ASS6 / Q8WZ42*ENSMUSG0000005174720
Hmcn1 / D3YXG0 / Hemicentin-1 / Q96RW7*ENSMUSG0000006684219
Hmcn2 / A2AJ76 / Hemicentin-2 / Q8NDA2*ENSMUSG0000005563219
Igsf10 / Q3V1M1 / Immunoglobulin superfamily member 10 / Q6WRI0*ENSMUSG000000363348
Mypn / Q5DTJ9 / Myopalladin / Q86TC9*ENSMUSG000000200672
Palld / Q9ET54 / Palladin / Q8WX93* / palladin, cytoskeletal associated protein*ENSMUSG000000580561
Myot / Q9JIF9 / myotilin / Q9UBF9*ENSMUSG000000244710


Protein motifs (from Interpro)
Interpro ID Name
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR003961  Fibronectin type III
 IPR007110  Immunoglobulin-like domain
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000226 microtubule cytoskeleton organization IEA
 biological_processGO:0006941 striated muscle contraction IBA
 biological_processGO:0007015 actin filament organization IBA
 biological_processGO:0007030 Golgi organization IEA
 biological_processGO:0007088 regulation of mitotic nuclear division IEA
 biological_processGO:0034067 protein localization to Golgi apparatus IEA
 biological_processGO:0045214 sarcomere organization IBA
 biological_processGO:0050775 positive regulation of dendrite morphogenesis IEA
 biological_processGO:0071688 striated muscle myosin thick filament assembly IBA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005859 muscle myosin complex IBA
 cellular_componentGO:0030018 Z disc IBA
 cellular_componentGO:0031430 M band IBA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:1990393 3M complex IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008307 structural constituent of muscle IBA
 molecular_functionGO:0051015 actin filament binding IBA
 molecular_functionGO:0051371 muscle alpha-actinin binding IBA
 molecular_functionGO:0097493 structural molecule activity conferring elasticity IBA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000010376 Nedd8 / P29595 / Q15843* / neural precursor cell expressed, developmentally down-regulated 8*  / reaction / complex
 ENSMUSG00000022400 Rbx1 / P62878 / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed / P62877* / ring-box 1*  / reaction / complex
 ENSMUSG00000038545 Cul7 / Q8VE73 / Cullin-7 / Q14999*  / complex
 ENSMUSG00000040327 Cul9 / cullin 9 / Q8IWT3*  / reaction / complex
 ENSMUSG00000041117 Ccdc8 / D3YZV8 / Coiled-coil domain-containing / Q9H0W5* / coiled-coil domain containing 8*  / complex






 

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