ENSMUSG00000067441


Mus musculus

Features
Gene ID: ENSMUSG00000067441
  
Biological name :H2afb1
  
Synonyms : H2afb1
  
Possible biological names infered from orthology : H2AFB2 / H2AFB3 / H2A histone family member B1 / H2A histone family member B2 / H2A histone family member B3 / P0C5Y9 / P0C5Z0
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: E1
Gene start: 117014757
Gene end: 117015104
  
Corresponding Affymetrix probe sets: 10601553 (MoGene1.0st)   10606552 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000138181
NCBI entrez gene - 100039319     See in Manteia.
MGI - MGI:3642445
RefSeq - NM_001102665
RefSeq Peptide - NP_001096135
swissprot - S4R1E0
Ensembl - ENSMUSG00000067441
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000015609Gallus gallus
 H2AFB1ENSG00000274183Homo sapiens
 H2AFB2ENSG00000277858Homo sapiens
 H2AFB3ENSG00000277745Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
H2afb3 / H2AFB2* / P0C5Z0* / H2AFB1* / P0C5Y9* / H2A histone family member B3* / H2A histone family member B1* / H2A histone family member B2*ENSMUSG0000008361697
H2afb2 / H2AFB3* / P0C5Z0* / H2AFB1* / P0C5Y9* / H2A histone family member B3* / H2A histone family member B1* / H2A histone family member B2*ENSMUSG0000008248282
Q64522 / Hist2h2ab / Histone H2A type 2-B / Q8IUE6* / histone cluster 2 H2A family member b*ENSMUSG0000006368937
Hist1h2aa / histone cluster 1, H2aa / Q96QV6* / histone cluster 1 H2A family member a*ENSMUSG0000006008137
H2afj / Q8R1M2 / Histone H2A.J / Q9BTM1* / H2A histone family member J*ENSMUSG0000006003237
H2afx / P27661 / Histone H2AX / P16104* / H2A histone family member X*ENSMUSG0000004993237
Q64523 / Hist2h2ac / Histone H2A type 2-C ENSMUSG0000006885536
Q6GSS7 / Hist2h2aa2 / Histone H2A type 2-A ENSMUSG0000006395436
Q6GSS7 / Hist2h2aa1 / Histone H2A type 2-A / Q16777* / Q6FI13* / HIST2H2AC* / HIST2H2AA4* / histone cluster 2 H2A family member c* / histone cluster 2 H2A family member a4*ENSMUSG0000006422036
Q8BFU2 / Hist3h2a / Histone H2A type 3 / Q7L7L0* / histone cluster 3 H2A*ENSMUSG0000007885136
Q8CGP5 / Hist1h2af / Histone H2A type 1-F ENSMUSG0000006199135
Q8CGP7 / Hist1h2ak / Histone H2A type 1-K ENSMUSG0000006302135
H2afy / Q9QZQ8 / Core histone macro-H2A.1 / O75367* / H2A histone family member Y*ENSMUSG0000001593730
H2afy2 / Q8CCK0 / Core histone macro-H2A.2 / Q9P0M6* / H2A histone family member Y2*ENSMUSG0000002008630


Protein motifs (from Interpro)
Interpro ID Name
 IPR002119  Histone H2A
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006342 chromatin silencing IBA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0000788 nuclear nucleosome ISO
 cellular_componentGO:0000790 nuclear chromatin IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0035327 transcriptionally active chromatin ISO
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Packaging Of Telomere Ends
Formation of the beta-catenin:TCF transactivating complex
PRC2 methylates histones and DNA
Condensation of Prophase Chromosomes
Oxidative Stress Induced Senescence
Senescence-Associated Secretory Phenotype (SASP)
DNA Damage/Telomere Stress Induced Senescence
RMTs methylate histone arginines
SIRT1 negatively regulates rRNA expression
NoRC negatively regulates rRNA expression
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Deposition of new CENPA-containing nucleosomes at the centromere
RNA Polymerase I Promoter Opening
RNA Polymerase I Chain Elongation
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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