MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap/Bglap2tm3.1Kry,Tg(Col1a1-cre)1Kry/0 Genetic Background: involves: FVB
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap2+,Gprc6atm1.1Kry/Gprc6a+,Tg(Cyp17a1-icre)AJako/0 Genetic Background: Not Specified
|
MP:0001552 | increased circulating triglyceride level | "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0001751 | increased circulating luteinizing hormone level | "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0002078 | abnormal glucose homeostasis | "anomaly in the state of equilibrium or processing in the body with respect to glucose in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0002079 | increased circulating insulin level | "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Lepob/Lepob,Ptprvtm1Asmi/Ptprv+ Genetic Background: involves: 129P2/OlaHsd * STOCK Mlphln a Tgfawa1 Cdh23v Ednrbs
|
MP:0002113 | abnormal skeleton development | "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0002687 | oligozoospermia | "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap/Bglap2tm3.1Kry,Tg(Col1a1-cre)1Kry/0 Genetic Background: involves: FVB
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap2+,Gprc6atm1.1Kry/Gprc6a+,Tg(Cyp17a1-icre)AJako/0 Genetic Background: Not Specified
|
MP:0002727 | decreased circulating insulin level | "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0002780 | decreased circulating testosterone level | "less than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap/Bglap2tm3.1Kry,Tg(Col1a1-cre)1Kry/0 Genetic Background: involves: FVB
|
MP:0002998 | abnormal bone remodeling | "aberrant process of the turnover of bone matrix that involves a balance of resorbtion and formation by osteoclasts and osteoblasts, respectively" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0003059 | decreased insulin secretion | "less than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0003795 | abnormal bone structure | |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0004148 | increased cortical bone thickness | "thicker than normal superficial layer of compact bone" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0004149 | increased bone strength | "increased ability of bone to endure the application of force without yielding or breaking" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0004214 | abnormal long bone diaphysis morphology | "any structural anomaly of the main or mid section (shaft) of a long bone" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0004852 | decreased testis weight | "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap/Bglap2tm3.1Kry,Tg(Col1a1-cre)1Kry/0 Genetic Background: involves: FVB
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap2+,Gprc6atm1.1Kry/Gprc6a+,Tg(Cyp17a1-icre)AJako/0 Genetic Background: Not Specified
|
MP:0004890 | decreased energy expenditure | "decrease in the number of calories used per unit time or increase in weight gain for a given amount of food eaten" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0004893 | decreased adiponectin level | "reduced concentration of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Adipoqtm1Ish/Adipoq+,Bglap/Bglap2tm1Kry/Bglap2+ Genetic Background: involves: 129S7/SvEvBrd
|
MP:0004910 | decreased seminal gland weight | "reduction in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap/Bglap2tm3.1Kry,Tg(Col1a1-cre)1Kry/0 Genetic Background: involves: FVB
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap2+,Gprc6atm1.1Kry/Gprc6a+,Tg(Cyp17a1-icre)AJako/0 Genetic Background: Not Specified
|
MP:0004929 | decreased epididymis weight | "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap/Bglap2tm3.1Kry,Tg(Col1a1-cre)1Kry/0 Genetic Background: involves: FVB
Allelic Composition: Bglap/Bglap2tm3.1Kry/Bglap2+,Gprc6atm1.1Kry/Gprc6a+,Tg(Cyp17a1-icre)AJako/0 Genetic Background: Not Specified
|
MP:0004984 | increased osteoclast cell number | "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0005182 | increased circulating estradiol level | "greater than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0005215 | abnormal islet of Langerhans morphology | "anomalous morphology of these structures that are scattered throughout the pancreas and comprise its endocrine portion; within each islet there are three cell types: alpha, beta, and delta " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0005293 | impaired glucose tolerance | "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0005331 | insulin resistance | "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Adipoqtm1Ish/Adipoq+,Bglap/Bglap2tm1Kry/Bglap2+ Genetic Background: involves: 129S7/SvEvBrd
|
MP:0005536 | Leydig cell hypoplasia | "reduced numbers of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0005559 | increased circulating glucose level | "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0005605 | increased bone mass | "an increase in the total amount of bone tissue contained in the skeleton" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0006379 | abnormal spermatocyte morphology | "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0006380 | abnormal spermatid morphology | "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0009114 | decreased pancreatic beta cell mass | "reduced total physical bulk or volume of a pancreatic beta cell compared to the normal state" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0009115 | abnormal fat cell morphology | "any structural anomaly of a fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0009168 | decreased pancreatic islet number | "reduction in the number of the clusters of hormone-producing cells that are scattered throughout the pancreas" [MA:0000127, MESH:A03.734.414] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0009172 | small pancreatic islets | "decrease in the size of the clusters of hormone-producing cells that are scattered throughout the pancreas" [MA:0000127, MESH:A03.734.414] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0009347 | increased cancellous bone thickness | "thicker than normal bone with a lattice-like or spongy structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Il3ram1/Il3ram1 Genetic Background: CE/J
|
MP:0010024 | increased total body fat amount | "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0011750 | abnormal seminiferous tubule epithelium morphology | "any structural anomaly of the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule" [MGI:csmith] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0011820 | decreased pancreatic beta cell proliferation | "reduction in the ability of the cells that secrete insulin and are located towards the center of the islets of Langerhans in the pancreas to undergo expansion by cell division" [CL:0000169] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|
MP:0030017 | decreased adipocyte glucose uptake | "reduced ability of adipocytes to take in glucose" [MGI:anna] |
Show
Allelic Composition: Ptprvtm1Asmi/Ptprvtm1Asmi Genetic Background: involves: 129P2/OlaHsd
|