ENSMUSG00000074489


Mus musculus

Features
Gene ID: ENSMUSG00000074489
  
Biological name :Bglap3
  
Synonyms : Bglap3 / Osteocalcin-related protein / P54615
  
Possible biological names infered from orthology : BGLAP / bone gamma-carboxyglutamate protein / P02818
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F1
Gene start: 88368616
Gene end: 88372743
  
Corresponding Affymetrix probe sets: 10499354 (MoGene1.0st)   10499358 (MoGene1.0st)   1449880_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000074965
Ensembl peptide - ENSMUSP00000103166
Ensembl peptide - ENSMUSP00000103167
NCBI entrez gene - 12095     See in Manteia.
MGI - MGI:88155
RefSeq - NM_001305450
RefSeq - NM_001305448
RefSeq - NM_001305449
RefSeq - NM_031368
RefSeq Peptide - NP_001292377
RefSeq Peptide - NP_001292378
RefSeq Peptide - NP_001292379
RefSeq Peptide - NP_112736
swissprot - P54615
Ensembl - ENSMUSG00000074489
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BGLAPENSGALG00000029494Gallus gallus
 BGLAPENSG00000242252Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Bglap2 / P86547 / Osteocalcin-2 / BGLAP* / P02818* / bone gamma-carboxyglutamate protein*ENSMUSG0000007448694
Bglap / P86546 / Osteocalcin / P02818* / bone gamma-carboxyglutamate protein*ENSMUSG0000007448391


Protein motifs (from Interpro)
Interpro ID Name
 IPR000294  Gamma-carboxyglutamic acid-rich (GLA) domain
 IPR002384  Osteocalcin/matrix Gla protein
 IPR035972  Gamma-carboxyglutamic acid-rich (GLA) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0030500 regulation of bone mineralization IEA
 biological_processGO:0031214 biomineral tissue development IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm ISO
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Gamma-carboxylation of protein precursors
Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
Removal of aminoterminal propeptides from gamma-carboxylated proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000053460 Ggcx / Q9QYC7 / Vitamin K-dependent gamma-carboxylase / P38435* / gamma-glutamyl carboxylase*  / reaction
 ENSMUSG00000030530 Furin / P23188 / P09958* / furin, paired basic amino acid cleaving enzyme*  / reaction






 

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