ENSMUSG00000076937


Mus musculus

Features
Gene ID: ENSMUSG00000076937
  
Biological name :Iglc2
  
Synonyms : Ig lambda-2 chain C region / Iglc2 / P01844
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A3
Gene start: 19198396
Gene end: 19200351
  
Corresponding Affymetrix probe sets: 1428719_at (Mouse Genome 430 2.0 Array)   1428720_s_at (Mouse Genome 430 2.0 Array)   1447918_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100464
Ensembl peptide - ENSMUSP00000143153
MGI - MGI:99547
swissprot - P01844
swissprot - Q99JC1
Ensembl - ENSMUSG00000076937
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CU571382.4ENSDARG00000110539Danio rerio
 FP016018.1ENSDARG00000093689Danio rerio
 FP016018.4ENSDARG00000111019Danio rerio
 IGLL1ENSGALG00000021139Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Iglc3ENSMUSG0000010554795
Iglc1 / IGLC3* / IGLC7* / IGLL1* / IGLC2* / IGLL5* / B9A064* / P0DOY2* / P0DOY3* / P15814* / immunoglobulin lambda constant 7* / immunoglobulin lambda constant 1* / immunoglobulin lambda co...ENSMUSG0000010590663
Iglc4 / IGLC2* / IGLC3* / IGLC7* / IGLL5* / IGLL1* / IGLC1* / B9A064* / P0DOY2* / P0DOY3* / P15814* / immunoglobulin lambda constant 7* / immunoglobulin lambda constant 1* / immunoglobulin ...ENSMUSG0000010603962
Igll1 / P20764 / Immunoglobulin lambda-like polypeptide 1 / IGLC3* / IGLC7* / IGLC2* / IGLL5* / IGLC1* / B9A064* / P0DOY2* / P0DOY3* / P15814* / immunoglobulin lambda constant 1* / immunog...ENSMUSG0000007537059
Igkc / immunoglobulin kappa constantENSMUSG0000007660938


Protein motifs (from Interpro)
Interpro ID Name
 IPR003006  Immunoglobulin/major histocompatibility complex, conserved site
 IPR003597  Immunoglobulin C1-set
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IBA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IEA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000003379 Cd79a / P11911 / B-cell antigen receptor complex-associated protein alpha chain / P11912* / CD79a molecule*  / complex
 ENSMUSG00000040592 Cd79b / P15530 / B-cell antigen receptor complex-associated protein beta chain / P40259* / CD79b molecule*  / complex






 

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contact: otassy@igbmc.fr