ENSDARG00000015002


Danio rerio

Features
Gene ID: ENSDARG00000015002
  
Biological name :cdh4
  
Synonyms : cadherin 4, type 1, R-cadherin (retinal) / cdh4
  
Possible biological names infered from orthology : cadherin 4 / P39038 / P55283
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 20371179
Gene end: 20826753
  
Corresponding Affymetrix probe sets: Dr.8115.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000134356
Ensembl peptide - ENSDARP00000094797
NCBI entrez gene - 30297     See in Manteia.
RefSeq - NM_131086
RefSeq - NM_001045273
RefSeq Peptide - NP_001038738
RefSeq Peptide - NP_571161
swissprot - A1L1M6
swissprot - Q1JQ39
ZFIN ID - ZDB-GENE-991207-1
Ensembl - ENSDARG00000015002
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDH4ENSGALG00000005102Gallus gallus
 CDH4ENSG00000179242Homo sapiens
 Cdh4ENSMUSG00000000305Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdh2 / cadherin 2, type 1, N-cadherin (neuronal) / P15116* / P19022* / cadherin 2*ENSDARG0000001869357
cdh1 / cdh30 / cadherin 1, type 1, E-cadherin (epithelial) / CDH3* / P22223* / P10287* / P12830* / cadherin 3* / cadherin 1*ENSDARG0000010275038
cdh31 / cadherin 31 / CDH1* / CDH3* / P22223* / P10287* / P12830* / cadherin 3* / cadherin 1*ENSDARG0000003579636
cdh15 / cadherin 15, type 1, M-cadherin (myotubule) / P33146* / P55291* / cadherin 15*ENSDARG0000006819133
si:dkey-30c15.12 / CDH1* / CDH3* / P10287* / P12830* / P22223* / cadherin 3* / cadherin 1*ENSDARG0000005854631
cdh28 / cadherin 28 / CDH3* / CDH1* / P22223* / P10287* / P12830* / cadherin 3* / cadherin 1*ENSDARG0000010433229
cdh13 / cadherin 13, H-cadherin (heart) / P55290* / Q9WTR5* / cadherin 13*ENSDARG0000001421528
dsc2l / desmocollin 2 like / DSC3* / DSC1* / DSC2* / Q14574* / P55850* / Q02487* / Q08554* / P55292* / P55849* / desmocollin 3* / desmocollin 2* / desmocollin 1*ENSDARG0000003967728
cdh30 / cadherin 30 / CDH1* / CDH3* / P22223* / P10287* / P12830* / cadherin 3* / cadherin 1*ENSDARG0000010444028
cdh26.2 / cadherin 26, tandem duplicate 2ENSDARG0000008764124
cdh27 / cadherin 27ENSDARG0000005509322
cdh26.1 / cadherin 26, tandem duplicate 1 / CDH26* / Q8IXH8* / P59862* / cadherin 26* / Cadherin-like protein 26 *ENSDARG0000007840421


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR014868  Cadherin prodomain
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0021545 cranial nerve development IMP
 biological_processGO:0042478 regulation of eye photoreceptor cell development IMP
 biological_processGO:0048593 camera-type eye morphogenesis IMP
 biological_processGO:0048925 lateral line system development IMP
 biological_processGO:0060042 retina morphogenesis in camera-type eye IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
CDO in myogenesis
Adherens junctions interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain disorganized , abnormal
Show

 ZFA:0000024 retinal ganglion cell layer retinal ganglion cell layer decreased thickness , abnormal
retinal ganglion cell layer disorganized , abnormal
retinal ganglion cell layer sparse , abnormal
retinal ganglion cell layer compartment boundary rough , abnormal
Show

 ZFA:0000029 hindbrain hindbrain decreased size , abnormal
Show

 ZFA:0000035 lens lens opaque , abnormal
lens decreased size , abnormal
lens apoptotic , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
eye shape , abnormal
Show

 ZFA:0000110 fourth ventricle fourth ventricle increased size , abnormal
Show

 ZFA:0000152 retina retina structure , abnormal
retina apoptotic , abnormal
retina lacks parts or has fewer parts of type photoreceptor cell , abnormal
retina lacks parts or has fewer parts of type amacrine cell , abnormal
retina hypoplastic , abnormal
Show

 ZFA:0000175 posterior lateral line nerve posterior lateral line nerve decreased length , abnormal
Show

 ZFA:0000243 neuromast neuromast decreased amount , abnormal
Show

 ZFA:0000435 cranial nerve II cranial nerve II truncated , abnormal
cranial nerve II sparse , abnormal
cranial nerve II decreased thickness , abnormal
cranial nerve II fasciculation , abnormal
Show

 ZFA:0000445 optic tectum optic tectum morphology , abnormal
Show

 ZFA:0000641 cranial nerve cranial nerve decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
Show

 ZFA:0001479 lateral line nerve lateral line nerve decreased size , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell neuron projection physical object quality , abnormal
retinal ganglion cell decreased amount , abnormal
retinal ganglion cell lacks parts or has fewer parts of type retinal ganglion cell neuron projection, abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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