ENSDARG00000039677


Danio rerio

Features
Gene ID: ENSDARG00000039677
  
Biological name :dsc2l
  
Synonyms : desmocollin 2 like / dsc2l
  
Possible biological names infered from orthology : desmocollin 1 / desmocollin 2 / desmocollin 3 / DSC1 / DSC2 / DSC3 / P55292 / P55849 / P55850 / Q02487 / Q08554 / Q14574
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 7262434
Gene end: 7293837
  
Corresponding Affymetrix probe sets: Dr.14617.1.S1_at (Zebrafish Array)   Dr.934.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000090832
swissprot - F1QSQ0
ZFIN ID - ZDB-GENE-031116-55
Ensembl - ENSDARG00000039677
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000015140Gallus gallus
 DSC1ENSG00000134765Homo sapiens
 DSC2ENSG00000134755Homo sapiens
 DSC3ENSG00000134762Homo sapiens
 Dsc1ENSMUSG00000044322Mus musculus
 Dsc2ENSMUSG00000024331Mus musculus
 Dsc3ENSMUSG00000059898Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cdh4 / cadherin 4, type 1, R-cadherin (retinal) / P39038* / P55283* / cadherin 4*ENSDARG0000001500228
cdh2 / cadherin 2, type 1, N-cadherin (neuronal) / P15116* / P19022* / cadherin 2*ENSDARG0000001869328
cdh1 / cdh30 / cadherin 1, type 1, E-cadherin (epithelial) / CDH3* / P22223* / P10287* / P12830* / cadherin 3* / cadherin 1*ENSDARG0000010275027
cdh31 / cadherin 31 / CDH1* / CDH3* / P22223* / P10287* / P12830* / cadherin 3* / cadherin 1*ENSDARG0000003579625
si:dkey-30c15.12 / CDH1* / CDH3* / P10287* / P12830* / P22223* / cadherin 3* / cadherin 1*ENSDARG0000005854623
cdh30 / cadherin 30 / CDH1* / CDH3* / P22223* / P10287* / P12830* / cadherin 3* / cadherin 1*ENSDARG0000010444023
cdh27 / cadherin 27ENSDARG0000005509322
cdh26.1 / cadherin 26, tandem duplicate 1 / CDH26* / Q8IXH8* / P59862* / cadherin 26* / Cadherin-like protein 26 *ENSDARG0000007840422
cdh26.2 / cadherin 26, tandem duplicate 2ENSDARG0000008764122
cdh28 / cadherin 28 / CDH3* / CDH1* / P22223* / P10287* / P12830* / cadherin 3* / cadherin 1*ENSDARG0000010433222
cdh15 / cadherin 15, type 1, M-cadherin (myotubule) / P33146* / P55291* / cadherin 15*ENSDARG0000006819121
cdh13 / cadherin 13, H-cadherin (heart) / P55290* / Q9WTR5* / cadherin 13*ENSDARG0000001421519


Protein motifs (from Interpro)
Interpro ID Name
 IPR000233  Cadherin, cytoplasmic domain
 IPR002126  Cadherin
 IPR009122  Desmosomal cadherin
 IPR009123  Desmoglein
 IPR014868  Cadherin prodomain
 IPR015919  Cadherin-like
 IPR020894  Cadherin conserved site
 IPR027397  Catenin binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002159 desmosome assembly IMP
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0055113 epiboly involved in gastrulation with mouth forming second IMP
 biological_processGO:0060027 convergent extension involved in gastrulation IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Keratinization
Formation of the cornified envelope


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000086 EVL EVL detached from E-YSL , abnormal
Show

 ZFA:0000114 heart heart desmosome structure , abnormal
heart desmosome decreased amount , abnormal
Show

 ZFA:0000135 notochord notochord kinked , abnormal
notochord undulate , abnormal
Show

 ZFA:0000155 somite somite absent , abnormal
somite morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
whole organism anterior-posterior axis decreased length , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved , abnormal
Show

 ZFA:0009183 epidermal cell epidermal cell desmosome decreased amount , abnormal
epidermal cell desmosome malformed , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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