ENSDARG00000016750


Danio rerio

Features
Gene ID: ENSDARG00000016750
  
Biological name :abcc6a
  
Synonyms : abcc6a / ATP-binding cassette, sub-family C (CFTR/MRP), member 6a
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 11026354
Gene end: 11067995
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000065432
Ensembl peptide - ENSDARP00000152529
NCBI entrez gene - 566555     See in Manteia.
RefSeq - XM_009302206
swissprot - E7F118
ZFIN ID - ZDB-GENE-050517-18
Ensembl - ENSDARG00000016750
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ABCC6ENSGALG00000038152Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abcc6b.2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2ENSDARG0000009490175
abcc1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 1 / O35379* / P33527* / ATP binding cassette subfamily C member 1*ENSDARG0000010471956
abcc3 / ATP-binding cassette, sub-family C (CFTR/MRP), member 3 / O15438* / ATP binding cassette subfamily C member 3*ENSDARG0000009666250
abcc6b.1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1ENSDARG0000010540347
abcc2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 2 / Q92887* / Q8VI47* / ATP binding cassette subfamily C member 2* / Canalicular multispecific organic anion transporter 1 *ENSDARG0000001403144
abcc10 / ATP-binding cassette, sub-family C (CFTR/MRP), member 10ENSDARG0000007798832
abcc8 / ATP-binding cassette, sub-family C (CFTR/MRP), member 8 / Q09428* / ATP binding cassette subfamily C member 8*ENSDARG0000005187930
abcc4 / ATP-binding cassette, sub-family C (CFTR/MRP), member 4 / O15439* / ATP binding cassette subfamily C member 4*ENSDARG0000005895330
abcc12 / ATP-binding cassette, sub-family C (CFTR/MRP), member 12 / Q96J66* / Q80WJ6* / Q96J65* / ABCC11* / ATP binding cassette subfamily C member 12* / ATP binding cassette subfamily C me...ENSDARG0000001305029
abcc9 / ATP-binding cassette, sub-family C (CFTR/MRP), member 9 / O60706* / P70170* / ATP binding cassette subfamily C member 9*ENSDARG0000001598529
abcc5 / ATP-binding cassette, sub-family C (CFTR/MRP), member 5 / O15440* / Q9R1X5* / ATP binding cassette subfamily C member 5* / Multidrug resistance-associated protein 5 *ENSDARG0000006123329
si:ch211-221f10.2ENSDARG0000007654729
abcc8b / ATP-binding cassette, sub-family C (CFTR/MRP), member 8b / ABCC8* / Q09428* / ATP binding cassette subfamily C member 8*ENSDARG0000007700729
cftr / Q1LX78 / cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) / P13569* / P26361* / cystic fibrosis transmembrane conductance regulator*ENSDARG0000004110724


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR005292  Multi drug resistance-associated protein
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030500 regulation of bone mineralization IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0055085 transmembrane transport IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
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 ZFA:0000368 integument integument mineralized , abnormal
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 ZFA:0000737 cranium cranium bone mineralization increased occurrence , abnormal
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 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism dead , abnormal
whole organism decreased size , abnormal
whole organism viability , abnormal
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 ZFA:0001115 trunk trunk curved , abnormal
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 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region curled , abnormal
post-vent region increased curvature , abnormal
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 ZFA:0001189 vertebra vertebra fused with vertebra , abnormal
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 ZFA:0001559 vertebral column vertebral column curved , abnormal
vertebral column anatomical space mineralized , abnormal
vertebral column bone mineralization increased occurrence , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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