ENSDARG00000077007


Danio rerio

Features
Gene ID: ENSDARG00000077007
  
Biological name :abcc8b
  
Synonyms : abcc8b / ATP-binding cassette, sub-family C (CFTR/MRP), member 8b
  
Possible biological names infered from orthology : ABCC8 / ATP binding cassette subfamily C member 8 / Q09428
  
Species: Danio rerio
  
Chr. number: 18
Strand: -1
Band:
Gene start: 50040849
Gene end: 50083408
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000089439
Ensembl peptide - ENSDARP00000136562
Ensembl peptide - ENSDARP00000153623
swissprot - A0A0N4SU49
swissprot - E7F108
ZFIN ID - ZDB-GENE-120215-45
Ensembl - ENSDARG00000077007
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ABCC8ENSGALG00000006172Gallus gallus
 ABCC8ENSG00000006071Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abcc8 / ATP-binding cassette, sub-family C (CFTR/MRP), member 8 / Q09428* / ATP binding cassette subfamily C member 8*ENSDARG0000005187977
abcc9 / ATP-binding cassette, sub-family C (CFTR/MRP), member 9 / O60706* / P70170* / ATP binding cassette subfamily C member 9*ENSDARG0000001598564
abcc3 / ATP-binding cassette, sub-family C (CFTR/MRP), member 3 / O15438* / ATP binding cassette subfamily C member 3*ENSDARG0000009666231
abcc1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 1 / O35379* / P33527* / ATP binding cassette subfamily C member 1*ENSDARG0000010471931
abcc2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 2 / Q92887* / Q8VI47* / ATP binding cassette subfamily C member 2* / Canalicular multispecific organic anion transporter 1 *ENSDARG0000001403130
abcc6b.2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2ENSDARG0000009490130
abcc6a / ATP-binding cassette, sub-family C (CFTR/MRP), member 6aENSDARG0000001675028
abcc10 / ATP-binding cassette, sub-family C (CFTR/MRP), member 10ENSDARG0000007798828
abcc4 / ATP-binding cassette, sub-family C (CFTR/MRP), member 4 / O15439* / ATP binding cassette subfamily C member 4*ENSDARG0000005895326
abcc12 / ATP-binding cassette, sub-family C (CFTR/MRP), member 12 / Q96J66* / Q80WJ6* / Q96J65* / ABCC11* / ATP binding cassette subfamily C member 12* / ATP binding cassette subfamily C me...ENSDARG0000001305025
abcc5 / ATP-binding cassette, sub-family C (CFTR/MRP), member 5 / O15440* / Q9R1X5* / ATP binding cassette subfamily C member 5* / Multidrug resistance-associated protein 5 *ENSDARG0000006123325
si:ch211-221f10.2ENSDARG0000007654725
cftr / Q1LX78 / cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) / P13569* / P26361* / cystic fibrosis transmembrane conductance regulator*ENSDARG0000004110721
abcc6b.1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1ENSDARG0000010540321


Protein motifs (from Interpro)
Interpro ID Name
 IPR000388  Sulphonylurea receptor
 IPR000844  ATP-binding cassette subfamily C member 8
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008281 sulfonylurea receptor activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
ATP sensitive Potassium channels
Regulation of insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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