ENSGALG00000016571


Gallus gallus

Features
Gene ID: ENSGALG00000016571
  
Biological name :GLRA2
  
Synonyms : GLRA2 / glycine receptor alpha 2
  
Possible biological names infered from orthology : Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA. / P23416 / Q7TNC8
  
Species: Gallus gallus
  
Chr. number: 1
Strand: -1
Band:
Gene start: 122392119
Gene end: 122516386
  
Corresponding Affymetrix probe sets: GgaAffx.10605.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000026696
Ensembl peptide - ENSGALP00000045441
NCBI entrez gene - 772019     See in Manteia.
RefSeq - XM_001234290
RefSeq - XM_003640518
RefSeq - XM_004934695
RefSeq - XM_004934696
swissprot - E1BTB5
swissprot - A0A1D5NYI3
Ensembl - ENSGALG00000016571
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GLRA2ENSG00000101958Homo sapiens
 Glra2ENSMUSG00000018589Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GLRA4 / glycine receptor alpha 4 / Q5JXX5* / Q61603* / Glycine receptor subunit alpha-4 *ENSGALG0000000493678
GLRA3 / glycine receptor alpha 3 / O75311*ENSGALG0000001078178
GLRA1 / glycine receptor alpha 1 / P23415* / Q64018* / Glycine receptor subunit alpha-1 *ENSGALG0000000413471
GLRB / glycine receptor beta / P48167* / P48168* / Glycine receptor subunit beta *ENSGALG0000000939548
GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *ENSGALG0000000169035
GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*ENSGALG0000002939235
GABRQ / P24045 / Gamma-aminobutyric acid receptor subunit beta-4 / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*ENSGALG0000003318335
GABRD / gamma-aminobutyric acid type A receptor delta subunit / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta *ENSGALG0000000128234
GABRR1 / gamma-aminobutyric acid type A receptor rho1 subunit / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 *ENSGALG0000001577833
GABRR2 / gamma-aminobutyric acid type A receptor rho2 subunit / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 *ENSGALG0000001577632
ENSGALG0000003168931
GABRP / gamma-aminobutyric acid type A receptor pi subunit / O00591* / Q8QZW7* / Gamma-aminobutyric acid receptor subunit pi *ENSGALG0000000215230
GABRR3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) / A8MPY1*ENSGALG0000003578730


Protein motifs (from Interpro)
Interpro ID Name
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR008127  Glycine receptor alpha
 IPR008129  Glycine receptor alpha2
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0043200 response to amino acid IBA
 biological_processGO:0060012 synaptic transmission, glycinergic IBA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0071230 cellular response to amino acid stimulus IEA
 biological_processGO:0071294 cellular response to zinc ion IEA
 biological_processGO:0071361 cellular response to ethanol IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0016594 glycine binding IEA
 molecular_functionGO:0016934 extracellularly glycine-gated chloride channel activity IBA
 molecular_functionGO:0022824 transmitter-gated ion channel activity IEA
 molecular_functionGO:0022852 glycine-gated chloride ion channel activity IEA


Pathways (from Reactome)
Pathway description
Neurotransmitter receptors and postsynaptic signal transmission


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000009395 GLRB / glycine receptor beta / P48167* / P48168* / Glycine receptor subunit beta *  / complex






 

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