Manteia

ENSGALG00000015776

Gallus gallus

Features

Gene ID:	ENSGALG00000015776

Biological name :	GABRR2

Synonyms :	GABRR2 / gamma-aminobutyric acid type A receptor rho2 subunit

Possible biological names infered from orthology :	Gamma-aminobutyric acid receptor subunit rho-2 / P28476 / P56476

Species:	Gallus gallus

Chr. number:	3
Strand:	1
Band:
Gene start:	75982576
Gene end:	76008365

Corresponding Affymetrix probe sets:	GgaAffx.10052.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000025397 NCBI entrez gene - 421815 See in Manteia. RefSeq - XM_015284702 RefSeq - XM_419839 swissprot - F1ND90 Ensembl - ENSGALG00000015776

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
gabrr2a	ENSDARG00000052982	Danio rerio
gabrr2b	ENSDARG00000014057	Danio rerio
GABRR2	ENSG00000111886	Homo sapiens
Gabrr2	ENSMUSG00000023267	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
GABRR1 / gamma-aminobutyric acid type A receptor rho1 subunit / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 *	ENSGALG00000015778	72
GABRR3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) / A8MPY1*	ENSGALG00000035787	59
GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*	ENSGALG00000029392	34
GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *	ENSGALG00000001690	33
GABRQ / P24045 / Gamma-aminobutyric acid receptor subunit beta-4 / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*	ENSGALG00000033183	32
GABRD / gamma-aminobutyric acid type A receptor delta subunit / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta *	ENSGALG00000001282	31
GABRP / gamma-aminobutyric acid type A receptor pi subunit / O00591* / Q8QZW7* / Gamma-aminobutyric acid receptor subunit pi *	ENSGALG00000002152	31
	ENSGALG00000031689	31
GLRA4 / glycine receptor alpha 4 / Q5JXX5* / Q61603* / Glycine receptor subunit alpha-4 *	ENSGALG00000004936	30
GLRB / glycine receptor beta / P48167* / P48168* / Glycine receptor subunit beta *	ENSGALG00000009395	29
GLRA3 / glycine receptor alpha 3 / O75311*	ENSGALG00000010781	29
GLRA2 / glycine receptor alpha 2 / P23416* / Q7TNC8* / Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA.*	ENSGALG00000016571	29
GLRA1 / glycine receptor alpha 1 / P23415* / Q64018* / Glycine receptor subunit alpha-1 *	ENSGALG00000004134	28

Protein motifs (from Interpro)

Interpro ID	Name
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
IPR006201	Neurotransmitter-gated ion-channel
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
IPR008057	Gamma-aminobutyric-acid A receptor, Rho
IPR008059	Gamma-aminobutyric-acid A receptor, Rho2
IPR018000	Neurotransmitter-gated ion-channel, conserved site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0007214	gamma-aminobutyric acid signaling pathway	IEA
biological_process	GO:0007601	visual perception	IEA
biological_process	GO:0034220	ion transmembrane transport	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:1902711	GABA-A receptor complex	IBA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0004890	GABA-A receptor activity	IBA
molecular_function	GO:0005216	ion channel activity	IEA
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity	IEA

Pathways (from Reactome)

Pathway description

GABA A (rho) receptor activation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000015778	GABRR1 / gamma-aminobutyric acid type A receptor rho1 subunit / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 *	/ complex
ENSGALG00000015776	GABRR2 / gamma-aminobutyric acid type A receptor rho2 subunit / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 *	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr