Manteia

ENSGALG00000001690

Gallus gallus

Features

Gene ID:	ENSGALG00000001690

Biological name :	GABRB2

Synonyms :	GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit

Possible biological names infered from orthology :	Gamma-aminobutyric acid receptor subunit beta-2 / P47870 / P63137

Species:	Gallus gallus

Chr. number:	13
Strand:	1
Band:
Gene start:	7347873
Gene end:	7480663

Corresponding Affymetrix probe sets:	Gga.733.1.A1_at (Chicken Array) Gga.733.1.S1_at (Chicken Array) Gga.734.1.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000054204 Ensembl peptide - ENSGALP00000002581 NCBI entrez gene - 414890 See in Manteia. RefSeq - XM_015293649 RefSeq - XM_015293645 RefSeq - XM_015293646 RefSeq - XM_015293648 RefSeq - NM_001277696 RefSeq - XM_015293643 RefSeq - XM_015293644 RefSeq Peptide - NP_001264625 swissprot - F6SVX7 swissprot - A0A1D5PMW7 Ensembl - ENSGALG00000001690

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
gabrb2	ENSDARG00000079586	Danio rerio
GABRB2 (1 of many)	ENSDARG00000100032	Danio rerio
GABRB2	ENSG00000145864	Homo sapiens
Gabrb2	ENSMUSG00000007653	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*	ENSGALG00000029392	76
GABRQ / P24045 / Gamma-aminobutyric acid receptor subunit beta-4 / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*	ENSGALG00000033183	68
GABRR1 / gamma-aminobutyric acid type A receptor rho1 subunit / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 *	ENSGALG00000015778	36
GABRD / gamma-aminobutyric acid type A receptor delta subunit / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta *	ENSGALG00000001282	35
	ENSGALG00000031689	35
GABRP / gamma-aminobutyric acid type A receptor pi subunit / O00591* / Q8QZW7* / Gamma-aminobutyric acid receptor subunit pi *	ENSGALG00000002152	34
GABRR3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) / A8MPY1*	ENSGALG00000035787	34
GLRA4 / glycine receptor alpha 4 / Q5JXX5* / Q61603* / Glycine receptor subunit alpha-4 *	ENSGALG00000004936	33
GLRA3 / glycine receptor alpha 3 / O75311*	ENSGALG00000010781	33
GABRR2 / gamma-aminobutyric acid type A receptor rho2 subunit / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 *	ENSGALG00000015776	33
GLRA2 / glycine receptor alpha 2 / P23416* / Q7TNC8* / Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA.*	ENSGALG00000016571	33
GLRA1 / glycine receptor alpha 1 / P23415* / Q64018* / Glycine receptor subunit alpha-1 *	ENSGALG00000004134	31
GLRB / glycine receptor beta / P48167* / P48168* / Glycine receptor subunit beta *	ENSGALG00000009395	31

Protein motifs (from Interpro)

Interpro ID	Name
IPR002289	Gamma-aminobutyric-acid A receptor, beta subunit
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
IPR006201	Neurotransmitter-gated ion-channel
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
IPR018000	Neurotransmitter-gated ion-channel, conserved site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007605	sensory perception of sound	IEA
biological_process	GO:0034220	ion transmembrane transport	IEA
biological_process	GO:0043523	regulation of neuron apoptotic process	IEA
biological_process	GO:0043524	negative regulation of neuron apoptotic process	IEA
biological_process	GO:0048666	neuron development	IEA
biological_process	GO:0060119	inner ear receptor cell development	IEA
biological_process	GO:0060384	innervation	IEA
biological_process	GO:0090102	cochlea development	IEA
biological_process	GO:1901215	negative regulation of neuron death	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:1902711	GABA-A receptor complex	IBA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0004890	GABA-A receptor activity	IEA
molecular_function	GO:0005216	ion channel activity	IEA
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity	IEA

Pathways (from Reactome)

Pathway description

GABA A receptor activation

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSGALG00000001690	GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *	/ complex
ENSGALG00000033183	GABRQ / P24045 / Gamma-aminobutyric acid receptor subunit beta-4 / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*	/ complex
ENSGALG00000038042	GABRG2 / P21548 / Gamma-aminobutyric acid receptor subunit gamma-2 / P22723* / P18507* / gamma-aminobutyric acid type A receptor gamma2 subunit*	/ complex
ENSGALG00000029392	GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*	/ complex

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr