ENSGALG00000029392


Gallus gallus

Features
Gene ID: ENSGALG00000029392
  
Biological name :GABRB3
  
Synonyms : GABRB3 / Gamma-aminobutyric acid receptor subunit beta-3 / P19019
  
Possible biological names infered from orthology : gamma-aminobutyric acid type A receptor beta3 subunit / P28472 / P63080
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 131393723
Gene end: 131503806
  
Corresponding Affymetrix probe sets: Gga.747.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050049
NCBI entrez gene - 396290     See in Manteia.
RefSeq - NM_205346
RefSeq Peptide - NP_990677
swissprot - P19019
Ensembl - ENSGALG00000029392
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GABRB3ENSG00000166206Homo sapiens
 Gabrb3ENSMUSG00000033676Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *ENSGALG0000000169078
GABRQ / P24045 / Gamma-aminobutyric acid receptor subunit beta-4 / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*ENSGALG0000003318372
GABRP / gamma-aminobutyric acid type A receptor pi subunit / O00591* / Q8QZW7* / Gamma-aminobutyric acid receptor subunit pi *ENSGALG0000000215236
GABRR1 / gamma-aminobutyric acid type A receptor rho1 subunit / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 *ENSGALG0000001577836
ENSGALG0000003168936
GABRD / gamma-aminobutyric acid type A receptor delta subunit / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta *ENSGALG0000000128235
GABRR2 / gamma-aminobutyric acid type A receptor rho2 subunit / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 *ENSGALG0000001577635
GLRA4 / glycine receptor alpha 4 / Q5JXX5* / Q61603* / Glycine receptor subunit alpha-4 *ENSGALG0000000493634
GABRR3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) / A8MPY1*ENSGALG0000003578734
GLRA3 / glycine receptor alpha 3 / O75311*ENSGALG0000001078133
GLRA2 / glycine receptor alpha 2 / P23416* / Q7TNC8* / Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA.*ENSGALG0000001657133
GLRA1 / glycine receptor alpha 1 / P23415* / Q64018* / Glycine receptor subunit alpha-1 *ENSGALG0000000413431
GLRB / glycine receptor beta / P48167* / P48168* / Glycine receptor subunit beta *ENSGALG0000000939531


Protein motifs (from Interpro)
Interpro ID Name
 IPR002289  Gamma-aminobutyric-acid A receptor, beta subunit
 IPR006028  Gamma-aminobutyric acid A receptor/Glycine receptor alpha
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007214 gamma-aminobutyric acid signaling pathway IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0043523 regulation of neuron apoptotic process IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IEA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0060021 roof of mouth development IEA
 biological_processGO:0060080 inhibitory postsynaptic potential IEA
 biological_processGO:0060119 inner ear receptor cell development IEA
 biological_processGO:0060384 innervation IEA
 biological_processGO:0071420 cellular response to histamine IEA
 biological_processGO:0090102 cochlea development IEA
 biological_processGO:1901215 negative regulation of neuron death IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:1902711 GABA-A receptor complex IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004890 GABA-A receptor activity IBA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity IEA
 molecular_functionGO:0022851 GABA-gated chloride ion channel activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
GABA A receptor activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000038042 GABRG2 / P21548 / Gamma-aminobutyric acid receptor subunit gamma-2 / P22723* / P18507* / gamma-aminobutyric acid type A receptor gamma2 subunit*  / complex
 ENSGALG00000001690 GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *  / complex
 ENSGALG00000033183 GABRQ / P24045 / Gamma-aminobutyric acid receptor subunit beta-4 / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*  / complex
 ENSGALG00000029392 GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*  / complex






 

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