ENSGALG00000009395


Gallus gallus

Features
Gene ID: ENSGALG00000009395
  
Biological name :GLRB
  
Synonyms : GLRB / glycine receptor beta
  
Possible biological names infered from orthology : Glycine receptor subunit beta / P48167 / P48168
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 21510760
Gene end: 21553448
  
Corresponding Affymetrix probe sets: Gga.14206.1.S1_s_at (Chicken Array)   GgaAffx.22910.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015289
NCBI entrez gene - 422411     See in Manteia.
RefSeq - XM_004940905
RefSeq - XM_015285340
RefSeq - XM_420379
swissprot - F1P037
Ensembl - ENSGALG00000009395
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 glrbaENSDARG00000052782Danio rerio
 glrbbENSDARG00000052769Danio rerio
 GLRBENSG00000109738Homo sapiens
 GlrbENSMUSG00000028020Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GLRA2 / glycine receptor alpha 2 / P23416* / Q7TNC8* / Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA.*ENSGALG0000001657144
GLRA3 / glycine receptor alpha 3 / O75311*ENSGALG0000001078143
GLRA4 / glycine receptor alpha 4 / Q5JXX5* / Q61603* / Glycine receptor subunit alpha-4 *ENSGALG0000000493642
GLRA1 / glycine receptor alpha 1 / P23415* / Q64018* / Glycine receptor subunit alpha-1 *ENSGALG0000000413438
GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *ENSGALG0000000169031
GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*ENSGALG0000002939230
GABRQ / P24045 / Gamma-aminobutyric acid receptor subunit beta-4 / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*ENSGALG0000003318329
GABRR2 / gamma-aminobutyric acid type A receptor rho2 subunit / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 *ENSGALG0000001577628
GABRR1 / gamma-aminobutyric acid type A receptor rho1 subunit / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 *ENSGALG0000001577828
GABRD / gamma-aminobutyric acid type A receptor delta subunit / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta *ENSGALG0000000128227
GABRP / gamma-aminobutyric acid type A receptor pi subunit / O00591* / Q8QZW7* / Gamma-aminobutyric acid receptor subunit pi *ENSGALG0000000215226
GABRR3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) / A8MPY1*ENSGALG0000003578726
ENSGALG0000003168925


Protein motifs (from Interpro)
Interpro ID Name
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR008060  Glycine receptor beta
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001964 startle response IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006821 chloride transport IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007340 acrosome reaction IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0007628 adult walking behavior IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0043200 response to amino acid IBA
 biological_processGO:0050905 neuromuscular process IEA
 biological_processGO:0060012 synaptic transmission, glycinergic IEA
 biological_processGO:0060013 righting reflex IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0097112 gamma-aminobutyric acid receptor clustering IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016935 glycine-gated chloride channel complex IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0098982 GABA-ergic synapse IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0016594 glycine binding IEA
 molecular_functionGO:0016933 extracellularly glycine-gated ion channel activity IEA
 molecular_functionGO:0016934 extracellularly glycine-gated chloride channel activity IBA


Pathways (from Reactome)
Pathway description
Neurotransmitter receptors and postsynaptic signal transmission


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016571 GLRA2 / glycine receptor alpha 2 / P23416* / Q7TNC8* / Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA.*  / complex






 

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