Manteia

ENSGALG00000004936

Gallus gallus

Features

Gene ID:	ENSGALG00000004936

Biological name :	GLRA4

Synonyms :	GLRA4 / glycine receptor alpha 4

Possible biological names infered from orthology :	Glycine receptor subunit alpha-4 / Q5JXX5 / Q61603

Species:	Gallus gallus

Chr. number:	4
Strand:	1
Band:
Gene start:	2023971
Gene end:	2030901

Corresponding Affymetrix probe sets:	Gga.6508.1.A1_at (Chicken Array) GgaAffx.26361.1.S1_s_at (Chicken Array) GgaAffx.26361.2.S1_at (Chicken Array)

Cross references:	Ensembl peptide - ENSGALP00000007885 NCBI entrez gene - 769706 See in Manteia. RefSeq - XM_015278389 RefSeq - XM_015278390 swissprot - F1NEM1 Ensembl - ENSGALG00000004936

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
glra4a	ENSDARG00000006865	Danio rerio
glra4b	ENSDARG00000058103	Danio rerio
GLRA4	ENSG00000188828	Homo sapiens
Glra4	ENSMUSG00000018595	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
GLRA2 / glycine receptor alpha 2 / P23416* / Q7TNC8* / Mus musculus glycine receptor, alpha 2 subunit (Glra2), transcript variant 3, mRNA.*	ENSGALG00000016571	76
GLRA3 / glycine receptor alpha 3 / O75311*	ENSGALG00000010781	73
GLRA1 / glycine receptor alpha 1 / P23415* / Q64018* / Glycine receptor subunit alpha-1 *	ENSGALG00000004134	69
GLRB / glycine receptor beta / P48167* / P48168* / Glycine receptor subunit beta *	ENSGALG00000009395	46
GABRB2 / gamma-aminobutyric acid type A receptor beta2 subunit / P47870* / P63137* / Gamma-aminobutyric acid receptor subunit beta-2 *	ENSGALG00000001690	36
GABRB3 / P19019 / Gamma-aminobutyric acid receptor subunit beta-3 / P63080* / P28472* / gamma-aminobutyric acid type A receptor beta3 subunit*	ENSGALG00000029392	35
GABRQ / P24045 / Gamma-aminobutyric acid receptor subunit beta-4 / Q9UN88* / Q9JLF1* / Gamma-aminobutyric acid receptor subunit theta * / gamma-aminobutyric acid type A receptor theta subunit*	ENSGALG00000033183	35
GABRD / gamma-aminobutyric acid type A receptor delta subunit / O14764* / P22933* / Gamma-aminobutyric acid receptor subunit delta *	ENSGALG00000001282	34
GABRR2 / gamma-aminobutyric acid type A receptor rho2 subunit / P28476* / P56476* / Gamma-aminobutyric acid receptor subunit rho-2 *	ENSGALG00000015776	32
GABRR1 / gamma-aminobutyric acid type A receptor rho1 subunit / P24046* / P56475* / Gamma-aminobutyric acid receptor subunit rho-1 *	ENSGALG00000015778	31
	ENSGALG00000031689	30
GABRP / gamma-aminobutyric acid type A receptor pi subunit / O00591* / Q8QZW7* / Gamma-aminobutyric acid receptor subunit pi *	ENSGALG00000002152	29
GABRR3 / gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene) / A8MPY1*	ENSGALG00000035787	29

Protein motifs (from Interpro)

Interpro ID	Name
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain
IPR006201	Neurotransmitter-gated ion-channel
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain
IPR008127	Glycine receptor alpha
IPR018000	Neurotransmitter-gated ion-channel, conserved site

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0006811	ion transport	IEA
biological_process	GO:0007218	neuropeptide signaling pathway	IBA
biological_process	GO:0034220	ion transmembrane transport	IEA
biological_process	GO:0043200	response to amino acid	IEA
biological_process	GO:0060012	synaptic transmission, glycinergic	IBA
biological_process	GO:0060079	excitatory postsynaptic potential	IEA
biological_process	GO:1902476	chloride transmembrane transport	IEA
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0005887	integral component of plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0098794	postsynapse	IEA
molecular_function	GO:0004888	transmembrane signaling receptor activity	IEA
molecular_function	GO:0005216	ion channel activity	IEA
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity	IEA
molecular_function	GO:0016594	glycine binding	IBA
molecular_function	GO:0016934	extracellularly glycine-gated chloride channel activity	IEA
molecular_function	GO:0022824	transmitter-gated ion channel activity	IEA

Pathways (from Reactome)

Pathway description

Neurotransmitter receptors and postsynaptic signal transmission

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr