ENSGALG00000029175


Gallus gallus

Features
Gene ID: ENSGALG00000029175
  
Biological name :EFNB2
  
Synonyms : EFNB2 / ephrin B2
  
Possible biological names infered from orthology : P52799 / P52800
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 141049589
Gene end: 141090557
  
Corresponding Affymetrix probe sets: Gga.13001.1.S1_s_at (Chicken Array)   Gga.13134.1.S1_at (Chicken Array)   Gga.357.1.S1_at (Chicken Array)   Gga.8369.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000042161
NCBI entrez gene - 395625     See in Manteia.
RefSeq - NM_204824
RefSeq Peptide - NP_990155
swissprot - Q9PUJ4
Ensembl - ENSGALG00000029175
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 efnb2aENSDARG00000020164Danio rerio
 efnb2bENSDARG00000074050Danio rerio
 EFNB2ENSG00000125266Homo sapiens
 Efnb2ENSMUSG00000001300Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EFNB1 / ephrin-B1 precursor / P52795* / P98172* / ephrin B1*ENSGALG0000003653951


Protein motifs (from Interpro)
Interpro ID Name
 IPR001799  Ephrin receptor-binding domain
 IPR008972  Cupredoxin
 IPR019765  Ephrin, conserved site
 IPR031328  Ephrin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001945 lymph vessel development IEA
 biological_processGO:0007411 axon guidance IBA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0010839 negative regulation of keratinocyte proliferation IEA
 biological_processGO:0016477 cell migration IBA
 biological_processGO:0031295 T cell costimulation IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IBA
 biological_processGO:0048514 blood vessel morphogenesis IEA
 biological_processGO:0048845 venous blood vessel morphogenesis IEA
 biological_processGO:0072178 nephric duct morphogenesis IEA
 biological_processGO:1903849 positive regulation of aorta morphogenesis IEA
 biological_processGO:2000727 positive regulation of cardiac muscle cell differentiation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0046875 ephrin receptor binding IBA


Pathways (from Reactome)
Pathway description
EPH-Ephrin signaling
EPHB-mediated forward signaling
Ephrin signaling
EPH-ephrin mediated repulsion of cells


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000681 PAK1 / p21 (RAC1) activated kinase 1 / Q13153* / Mus musculus p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), transcript variant 3, mRNA.*  / complex / reaction
 ENSGALG00000004741 EPHB2 / EPH receptor B2 / P29323* / P54763* / Ephrin type-B receptor 2 *  / - / complex / reaction
 ENSGALG00000008058 PAK3 / p21 (RAC1) activated kinase 3 / O75914* / Q61036* / Serine/threonine-protein kinase PAK 3 *  / complex / reaction
 ENSGALG00000007130 RAC1 / Rac family small GTPase 1 / P63000* / P63001* / RAS-related C3 botulinum substrate 1*  / reaction / complex
 ENSGALG00000006609 EPHB1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *  / - / complex / reaction
 ENSGALG00000009621 ACTB / P60706 / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / P60709* / P60710* / actin beta*  / complex / reaction
 ENSGALG00000015842 TIAM1 / T cell lymphoma invasion and metastasis 1 / Q13009*  / complex / reaction
 ENSGALG00000003855 SRC / P00523 / Proto-oncogene tyrosine-protein kinase Src / P12931* / P05480* / Neuronal proto-onco tyrosine-protein kinase Src * / SRC proto-oncogene, non-receptor tyrosine kinase*  / complex / reaction
 ENSGALG00000004796 CDC42 / Q90694 / Cell division control protein 42 homolog / P60766* / P60953* / cell division cycle 42* / Cell division control *  / complex
 ENSGALG00000014923 ARHGEF28 / Rho guanine nucleotide exchange factor 28 / Q8N1W1*  / complex / reaction
 ENSGALG00000015022 FYN / tyrosine-protein kinase Fyn / P06241* / P39688* / FYN proto-oncogene, Src family tyrosine kinase*  / complex / reaction
 ENSGALG00000014860 YES1 / P09324 / Tyrosine-protein kinase Yes / Q04736* / P07947* / YES proto-oncogene 1, Src family tyrosine kinase*  / complex
 ENSGALG00000017706 RASA1* / P20936* / RAS p21 protein activator 1*  / complex
 ENSGALG00000015436 SDCBP / syndecan binding protein / O00560* / O08992*  / complex / reaction
 ENSGALG00000000280 EFNA5 / ephrin-A5 precursor / O08543* / P52803* / ephrin A5*  / reaction
 ENSGALG00000008898 GRIN1 / glutamate ionotropic receptor NMDA type subunit 1 / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 *  / complex
 ENSGALG00000029175 EFNB2 / ephrin B2 / P52799* / P52800*  / - / complex / reaction
 ENSGALG00000029260 H-RAS / P08642 / GTPase HRas GTPase HRas, N-terminally processed / HRAS* / Q61411* / P01112* / HRas proto-oncogene, GTPase*  / complex / reaction
 ENSGALG00000042321 LYN / LYN proto-oncogene, Src family tyrosine kinase / P07948* / P25911*  / complex
 ENSGALG00000031741 PTK2 / Q00944 / Focal adhesion kinase 1 / P34152* / Q05397* / protein tyrosine kinase 2* / PTK2 protein tyrosine kinase 2*  / complex
 ENSGALG00000039327 VAV3 / vav guanine nucleotide exchange factor 3 / Q9R0C8* / Q9UKW4* / vav 3 oncogene*  / complex / reaction
 ENSGALG00000023703 GIT1 / GIT ArfGAP 1 / Q68FF6* / Q9Y2X7* / ARF GTPase-activating protein GIT1 *  / complex / reaction






 

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