ENSMUSG00000010110


Mus musculus

Features
Gene ID: ENSMUSG00000010110
  
Biological name :Stx5a
  
Synonyms : Q8K1E0 / Stx5a / Syntaxin-5
  
Possible biological names infered from orthology : Q13190 / STX5
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 8741413
Gene end: 8756069
  
Corresponding Affymetrix probe sets: 10461176 (MoGene1.0st)   1448267_at (Mouse Genome 430 2.0 Array)   1449679_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000134951
Ensembl peptide - ENSMUSP00000135348
Ensembl peptide - ENSMUSP00000135416
Ensembl peptide - ENSMUSP00000135465
Ensembl peptide - ENSMUSP00000135624
Ensembl peptide - ENSMUSP00000010254
Ensembl peptide - ENSMUSP00000073136
Ensembl peptide - ENSMUSP00000134794
Ensembl peptide - ENSMUSP00000134854
Ensembl peptide - ENSMUSP00000134892
Ensembl peptide - ENSMUSP00000135468
NCBI entrez gene - 56389     See in Manteia.
MGI - MGI:1928483
RefSeq - NM_001167799
RefSeq - NM_019829
RefSeq Peptide - NP_001161271
RefSeq Peptide - NP_062803
swissprot - Q8K1E0
swissprot - H3BJ02
swissprot - H3BJ89
swissprot - H3BJE3
swissprot - H3BKD6
swissprot - H3BKJ7
swissprot - H3BKP0
swissprot - H3BKP3
swissprot - H3BL25
swissprot - I1E4X1
Ensembl - ENSMUSG00000010110
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stx5aENSDARG00000025033Danio rerio
 stx5alENSDARG00000003175Danio rerio
 STX5ENSG00000162236Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000727  Target SNARE coiled-coil homology domain
 IPR006012  Syntaxin/epimorphin, conserved site
 IPR010989  SNARE
 IPR021538  Syntaxin-5, N-terminal, Sly1p-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0006906 vesicle fusion IBA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0034498 early endosome to Golgi transport ISO
 biological_processGO:0042147 retrograde transport, endosome to Golgi ISO
 biological_processGO:0045732 positive regulation of protein catabolic process ISO
 biological_processGO:0048278 vesicle docking IBA
 biological_processGO:0048280 vesicle fusion with Golgi apparatus IEA
 biological_processGO:0061025 membrane fusion IEA
 biological_processGO:0090166 Golgi disassembly ISO
 biological_processGO:1903358 regulation of Golgi organization ISO
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031201 SNARE complex IBA
 cellular_componentGO:0031982 vesicle ISO
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 molecular_functionGO:0000149 SNARE binding IBA
 molecular_functionGO:0005484 SNAP receptor activity IEA
 molecular_functionGO:0045296 cadherin binding ISO
 molecular_functionGO:0047485 protein N-terminus binding ISO


Pathways (from Reactome)
Pathway description
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-mediated anterograde transport
Intra-Golgi traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002741 Ykt6 / Q9CQW1 / YKT6 v-SNARE homolog (S. cerevisiae) / O15498* / YKT6 v-SNARE homolog*  / complex
 ENSMUSG00000006024 Napa / Q9DB05 / Alpha-soluble NSF attachment protein / P54920* / NSF attachment protein alpha*  / complex / reaction
 ENSMUSG00000010392 Gosr1 / O88630 / golgi SNAP receptor complex member 1 / O95249*  / complex / reaction
 ENSMUSG00000020952 Scfd1 / Q8BRF7 / Sec1 family domain-containing protein 1 / Q8WVM8* / sec1 family domain containing 1*  / complex
 ENSMUSG00000025484 Bet1l / O35153 / BET1-like protein / Q9NYM9* / Bet1 golgi vesicular membrane trafficking protein like*  / complex
 ENSMUSG00000020946 Gosr2 / O35166 / golgi SNAP receptor complex member 2 / O14653* / AC005670.2*  / complex
 ENSMUSG00000027879 O08547 / Sec22b / Vesicle-trafficking protein SEC22b / O75396* / SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)*  / complex / reaction
 ENSMUSG00000029407 Uso1 / Q9Z1Z0 / USO1 vesicle docking factor / O60763* / USO1 vesicle transport factor*  / reaction
 ENSMUSG00000034187 Nsf / P46460 / Vesicle-fusing ATPase / P46459* / N-ethylmaleimide sensitive factor, vesicle fusing ATPase*  / complex / reaction
 ENSMUSG00000032513 Q91X51 / Gorasp1 / golgi reassembly stacking protein 1 / Q9BQQ3*  / reaction
 ENSMUSG00000039234 Sec24d / Sec24 related gene family, member D (S. cerevisiae) / O94855* / SEC24 homolog D, COPII coat complex component*  / complex / reaction
 ENSMUSG00000032757 Bet1 / O35623 / BET1 homolog / O15155* / Bet1 golgi vesicular membrane trafficking protein*  / complex
 ENSMUSG00000002546 Golga2 / Q921M4 / golgi autoantigen, golgin subfamily a, 2 / A7E2F4* / A8MQT2* / D6RF30* / F8WBI6* / A6NCC3* / A6NDK9* / A6NDN3* / A6NMD2* / H3BSY2* / I6L899* / P0CG33* / P0CJ92* / Q08379* ...  / reaction
 ENSMUSG00000020986 Q01405 / Sec23a / Protein transport protein Sec23A / Q15436* / Sec23 homolog A, coat complex II component*  / complex / reaction
 ENSMUSG00000021192 Golga5 / Q9QYE6 / golgi autoantigen, golgin subfamily a, 5 / Q8TBA6* / golgin A5*  / reaction
 ENSMUSG00000034109 Golim4 / Q8BXA1 / golgi integral membrane protein 4 / O00461*  / reaction






 

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