ENSMUSG00000020021


Mus musculus

Features
Gene ID: ENSMUSG00000020021
  
Biological name :Fgd6
  
Synonyms : Fgd6 / FYVE, RhoGEF and PH domain-containing protein 6 / Q69ZL1
  
Possible biological names infered from orthology : FYVE, RhoGEF and PH domain containing 6 / Q6ZV73
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C2
Gene start: 94036001
Gene end: 94145339
  
Corresponding Affymetrix probe sets: 10365845 (MoGene1.0st)   1419322_at (Mouse Genome 430 2.0 Array)   1435467_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020208
NCBI entrez gene - 13998     See in Manteia.
MGI - MGI:1261419
RefSeq - NM_053072
RefSeq - XM_006513214
RefSeq Peptide - NP_444302
swissprot - Q69ZL1
Ensembl - ENSMUSG00000020021
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgd6ENSDARG00000045528Danio rerio
 FGD6ENSGALG00000011342Gallus gallus
 FGD6ENSG00000180263Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fgd5 / FYVE, RhoGEF and PH domain containing 5 / Q6ZNL6*ENSMUSG0000003403728
Fgd1 / P52734 / FYVE, RhoGEF and PH domain-containing protein 1 / P98174* / FYVE, RhoGEF and PH domain containing 1*ENSMUSG0000002526517
Fgd4 / Q91ZT5 / FYVE, RhoGEF and PH domain-containing protein 4 / Q96M96* / FYVE, RhoGEF and PH domain containing 4*ENSMUSG0000002278814
Fgd3 / FYVE, RhoGEF and PH domain containing 3 / Q5JSP0*ENSMUSG0000003794613
Fgd2 / Q8BY35 / FYVE, RhoGEF and PH domain-containing protein 2 / Q7Z6J4* / FYVE, RhoGEF and PH domain containing 2*ENSMUSG0000002401312
Q91WB4 / Plekhf2 / Pleckstrin homology domain-containing family F member 2 / Q9H8W4* / pleckstrin homology and FYVE domain containing 2*ENSMUSG000000499696
Q3TB82 / Plekhf1 / Pleckstrin homology domain-containing family F member 1 / Q96S99* / pleckstrin homology and FYVE domain containing 1*ENSMUSG000000741706


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000306  FYVE zinc finger
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008150 biological_process ND
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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