ENSMUSG00000037946


Mus musculus

Features
Gene ID: ENSMUSG00000037946
  
Biological name :Fgd3
  
Synonyms : Fgd3 / FYVE, RhoGEF and PH domain containing 3
  
Possible biological names infered from orthology : Q5JSP0
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: A5
Gene start: 49261554
Gene end: 49320311
  
Corresponding Affymetrix probe sets: 10409170 (MoGene1.0st)   1433398_at (Mouse Genome 430 2.0 Array)   1450235_at (Mouse Genome 430 2.0 Array)   1454593_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000048692
Ensembl peptide - ENSMUSP00000105713
Ensembl peptide - ENSMUSP00000105714
NCBI entrez gene - 30938     See in Manteia.
MGI - MGI:1353657
RefSeq - XM_006516931
RefSeq - NM_015759
RefSeq - XM_006516929
RefSeq - XM_006516930
RefSeq Peptide - NP_056574
swissprot - A0A0R4J1D9
swissprot - Q3TNB8
Ensembl - ENSMUSG00000037946
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01079663.1ENSDARG00000099650Danio rerio
 FGD3ENSGALG00000005237Gallus gallus
 FGD3ENSG00000127084Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fgd1 / P52734 / FYVE, RhoGEF and PH domain-containing protein 1 / P98174* / FYVE, RhoGEF and PH domain containing 1*ENSMUSG0000002526547
Fgd4 / Q91ZT5 / FYVE, RhoGEF and PH domain-containing protein 4 / Q96M96* / FYVE, RhoGEF and PH domain containing 4*ENSMUSG0000002278838
Fgd2 / Q8BY35 / FYVE, RhoGEF and PH domain-containing protein 2 / Q7Z6J4* / FYVE, RhoGEF and PH domain containing 2*ENSMUSG0000002401333
Fgd6 / Q69ZL1 / FYVE, RhoGEF and PH domain-containing protein 6 / Q6ZV73* / FYVE, RhoGEF and PH domain containing 6*ENSMUSG0000002002124
Fgd5 / FYVE, RhoGEF and PH domain containing 5 / Q6ZNL6*ENSMUSG0000003403723
Q91WB4 / Plekhf2 / Pleckstrin homology domain-containing family F member 2 / Q9H8W4* / pleckstrin homology and FYVE domain containing 2*ENSMUSG000000499698
Q3TB82 / Plekhf1 / Pleckstrin homology domain-containing family F member 1 / Q96S99* / pleckstrin homology and FYVE domain containing 1*ENSMUSG000000741708


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000306  FYVE zinc finger
 IPR001849  Pleckstrin homology domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR035899  Dbl homology (DH) domain superfamily
 IPR035941  FGD1-4, C-terminal PH domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr