ENSMUSG00000034037


Mus musculus

Features
Gene ID: ENSMUSG00000034037
  
Biological name :Fgd5
  
Synonyms : Fgd5 / FYVE, RhoGEF and PH domain containing 5
  
Possible biological names infered from orthology : Q6ZNL6
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: D1
Gene start: 91978878
Gene end: 92076004
  
Corresponding Affymetrix probe sets: 10540168 (MoGene1.0st)   10343536 (MoGene1.0st)   1460578_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000086748
Ensembl peptide - ENSMUSP00000109093
NCBI entrez gene - 232237     See in Manteia.
MGI - MGI:2443369
RefSeq - NM_172731
RefSeq - XM_006506000
RefSeq Peptide - NP_766319
swissprot - E9QLU9
swissprot - E9QKY4
Ensembl - ENSMUSG00000034037
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgd5aENSDARG00000088801Danio rerio
 fgd5bENSDARG00000089622Danio rerio
 FGD5ENSGALG00000008546Gallus gallus
 FGD5ENSG00000154783Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fgd6 / Q69ZL1 / FYVE, RhoGEF and PH domain-containing protein 6 / Q6ZV73* / FYVE, RhoGEF and PH domain containing 6*ENSMUSG0000002002126
Fgd1 / P52734 / FYVE, RhoGEF and PH domain-containing protein 1 / P98174* / FYVE, RhoGEF and PH domain containing 1*ENSMUSG0000002526513
Fgd4 / Q91ZT5 / FYVE, RhoGEF and PH domain-containing protein 4 / Q96M96* / FYVE, RhoGEF and PH domain containing 4*ENSMUSG0000002278812
Fgd3 / FYVE, RhoGEF and PH domain containing 3 / Q5JSP0*ENSMUSG0000003794611
Fgd2 / Q8BY35 / FYVE, RhoGEF and PH domain-containing protein 2 / Q7Z6J4* / FYVE, RhoGEF and PH domain containing 2*ENSMUSG0000002401310
Q3TB82 / Plekhf1 / Pleckstrin homology domain-containing family F member 1 / Q96S99* / pleckstrin homology and FYVE domain containing 1*ENSMUSG000000741705
Q91WB4 / Plekhf2 / Pleckstrin homology domain-containing family F member 2 / Q9H8W4* / pleckstrin homology and FYVE domain containing 2*ENSMUSG000000499694


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR000306  FYVE zinc finger
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Bmp4tm4Blh/Bmp4+,Bmp7tm1.1Dgra/Bmp7tm1.1Dgra,Hoxa3tm1(cre)Moon/Hoxa3+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac

Allelic Composition: Fgd5tm2Djr/Fgd5tm2Djr
Genetic Background: involves: C57BL/6NTac

Allelic Composition: Fgd5tm3(cre/ERT2)Djr/Fgd5tm3(cre/ERT2)Djr
Genetic Background: involves: C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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