ENSMUSG00000057037


Mus musculus

Features
Gene ID: ENSMUSG00000057037
  
Biological name :Cfhr1
  
Synonyms : Cfhr1 / complement factor H-related 1
  
Possible biological names infered from orthology : BX248415.1 / CFHR2 / CFHR5 / complement factor H related 2 / complement factor H related 5 / P36980 / Q03591 / Q9BXR6
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: F
Gene start: 139547053
Gene end: 139560272
  
Corresponding Affymetrix probe sets: 10358315 (MoGene1.0st)   1419436_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142078
Ensembl peptide - ENSMUSP00000023965
NCBI entrez gene - 50702     See in Manteia.
MGI - MGI:2138169
RefSeq - NM_015780
RefSeq Peptide - NP_056595
swissprot - A0A0A6YXP6
swissprot - Q61406
Ensembl - ENSMUSG00000057037
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000002431Gallus gallus
 BX248415.1ENSG00000276911Homo sapiens
 CFHR1ENSG00000244414Homo sapiens
 CFHR2ENSG00000080910Homo sapiens
 CFHR5ENSG00000134389Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cfh / P06909 / Complement factor H / CFHR3* / CFHR4* / Q92496* / P08603* / Q02985* / complement factor H related 4* / complement factor H related 3*ENSMUSG0000002636544
Cfhr2 / complement factor H-related 2 / CFH* / CFHR3* / CFHR4* / Q92496* / P08603* / Q02985* / complement factor H* / complement factor H related 4* / complement factor H related 3*ENSMUSG0000003389841
Gm4788 / complement factor H-related protein C isoform 2 / CFH* / CFHR4* / CFHR3* / Q92496* / P08603* / Q02985* / complement factor H* / complement factor H related 3* / complement factor ...ENSMUSG0000007059439
F13b / Q07968 / Coagulation factor XIII B chain / P05160*ENSMUSG0000002636824
Zp3r / zona pellucida 3 receptorENSMUSG0000004255416
C4bp / P08607 / C4b-binding protein ENSMUSG0000002640514
Selp / Q01102 / selectin, platelet / P16109* / selectin P*ENSMUSG0000002658014
Sele / selectin, endothelial cell / P16581* / selectin E*ENSMUSG0000002658212
Cd55 / Q61475 / Complement decay-accelerating factor, GPI-anchored / P08174* / CD55 molecule (Cromer blood group)*ENSMUSG0000002639911
Cd55b / CD55* / P08174* / CD55 molecule (Cromer blood group)*ENSMUSG0000002640111
Apoh / Q01339 / Beta-2-glycoprotein 1 / P02749* / apolipoprotein H*ENSMUSG0000000004910
Sell / P18337 / selectin, lymphocyte / P14151* / selectin L*ENSMUSG0000002658110
Cd46 / O88174 / Membrane cofactor protein / P15529* / CD46 molecule*ENSMUSG000000164938


Protein motifs (from Interpro)
Interpro ID Name
 IPR000436  Sushi/SCR/CCP domain
 IPR035976  Sushi/SCR/CCP superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032091 negative regulation of protein binding ISO
 biological_processGO:0045919 positive regulation of cytolysis ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO


Pathways (from Reactome)
Pathway description
Regulation of Complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000057037 Cfhr1 / complement factor H-related 1 / CFHR5* / CFHR2* / P36980* / Q9BXR6* / Q03591* / BX248415.1* / complement factor H related 5* / complement factor H related 2*  / complex
 ENSMUSG00000024164 C3 / P01027 / Complement C3 Complement C3 beta chain C3-beta-c Complement C3 alpha chain C3a anaphylatoxin Acylation stimulating protein Complement C3b alpha chain Complement C3c alpha chain...  / complex / reaction






 

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