ENSMUSG00000075224


Mus musculus
potassiumchannelLrrc55leucine-richrepeationvoltage-gatedactivitymembranedomaintransportbindingn-terminalcysteine-richflankingregionc-terminaltypicalsubtypesuperfamilyaxonogenesistransmembraneregulationextracellularspaceplasmacomplexintegralcomponentproteinactivator

Features
Gene ID: ENSMUSG00000075224
  
Biological name :Lrrc55
  
Synonyms : Leucine-rich repeat-containing protein 55 / Lrrc55 / Q3UY51
  
Possible biological names infered from orthology : leucine rich repeat containing 55 / Q6ZSA7
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: D
Gene start: 85162334
Gene end: 85196699
  
Corresponding Affymetrix probe sets: 10484503 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000097514
Ensembl peptide - ENSMUSP00000107228
NCBI entrez gene - 241528     See in Manteia.
MGI - MGI:2685197
RefSeq - XM_006499469
RefSeq - NM_001033346
RefSeq - XM_006499467
RefSeq - XM_006499468
RefSeq Peptide - NP_001028518
swissprot - Q3UY51
Ensembl - ENSMUSG00000075224
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LRRC55ENSGALG00000029130Gallus gallus
 LRRC55ENSG00000183908Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A2VDH3 / Lrrc38 / Leucine-rich repeat-containing protein 38 / Q5VT99* / leucine rich repeat containing 38*ENSMUSG0000002858433
Lrrc26 / Q91W20 / Leucine-rich repeat-containing protein 26 / Q2I0M4* / leucine rich repeat containing 26*ENSMUSG0000002696129
Lrrc24 / Q8BHA1 / Leucine-rich repeat-containing protein 24 / Q50LG9* / leucine rich repeat containing 24*ENSMUSG0000003370728
Lrrc52 / Q5M8M9 / Leucine-rich repeat-containing protein 52 / Q8N7C0* / leucine rich repeat containing 52*ENSMUSG0000004048528
Q7M6Z0 / Rtn4rl2 / Reticulon-4 receptor-like 2 / Q86UN3*ENSMUSG0000005089628
Lrtm2 / Q8BGX3 / Leucine-rich repeat and transmembrane domain-containing protein 2 / Q8N967* / leucine rich repeats and transmembrane domains 2*ENSMUSG0000005500328
Rtn4r / Q99PI8 / Reticulon-4 receptor / Q9BZR6*ENSMUSG0000004381124
Lrtm1 / Q8BXQ3 / Leucine-rich repeat and transmembrane domain-containing protein 1 / Q9HBL6* / leucine rich repeats and transmembrane domains 1*ENSMUSG0000004577624
Q8K0S5 / Rtn4rl1 / Reticulon-4 receptor-like 1 / Q86UN2*ENSMUSG0000004528723


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
establishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizationcellular component organizationanatomical structure developmentcellular developmental processregulation of molecular functionestablishment of localizatioestablishment of localizationcellular component organizatcellular component organizationanatomical structure developanatomical structure developmentcellular developmental procecellular developmental processregulation of molecular funcregulation of molecular function
transmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activityprotein bindingchannel regulator activitytransmembrane transporter activitytransmembrane transporter activityprotein bindingprotein bindingchannel regulator activitychannel regulator activity
extracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regioncellmembraneprotein-containing complexextracellular regionextracellular regioncellcellmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007409 axonogenesis IBA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:1903818 positive regulation of voltage-gated potassium channel activity IEA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0099104 potassium channel activator activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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