ENSDARG00000006392


Danio rerio

Features
Gene ID: ENSDARG00000006392
  
Biological name :exosc9
  
Synonyms : exosc9 / exosome component 9
  
Possible biological names infered from orthology : Exosome complex component RRP45 / Q06265 / Q9JHI7
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 19083501
Gene end: 19092155
  
Corresponding Affymetrix probe sets: Dr.18150.1.S1_at (Zebrafish Array)   NM_001006077_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000113428
Ensembl peptide - ENSDARP00000005262
NCBI entrez gene - 450057     See in Manteia.
RefSeq - NM_001006077
RefSeq Peptide - NP_001006077
swissprot - E9QJM6
swissprot - Q5XJQ5
ZFIN ID - ZDB-GENE-041010-180
Ensembl - ENSDARG00000006392
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EXOSC9ENSGALG00000011884Gallus gallus
 EXOSC9ENSG00000123737Homo sapiens
 Exosc9ENSMUSG00000027714Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
exosc7 / exosome component 7 / Q15024*ENSDARG0000010006020
exosc8 / exosome component 8 / Q96B26* / Q9D753* / Exosome complex component RRP43 *ENSDARG0000006875516


Protein motifs (from Interpro)
Interpro ID Name
 IPR001247  Exoribonuclease, phosphorolytic domain 1
 IPR015847  Exoribonuclease, phosphorolytic domain 2
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027408  PNPase/RNase PH domain superfamily
 IPR033100  Exosome complex component RRP45


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000467 exonucleolytic trimming to generate mature 3"-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3"-5" IBA
 biological_processGO:0034473 U1 snRNA 3"-end processing IBA
 biological_processGO:0034475 U4 snRNA 3"-end processing IBA
 biological_processGO:0034476 U5 snRNA 3"-end processing IBA
 biological_processGO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay IBA
 biological_processGO:0071028 nuclear mRNA surveillance IBA
 biological_processGO:0071035 nuclear polyadenylation-dependent rRNA catabolic process IBA
 biological_processGO:0071038 nuclear polyadenylation-dependent tRNA catabolic process IBA
 biological_processGO:0071042 nuclear polyadenylation-dependent mRNA catabolic process IBA
 cellular_componentGO:0000176 nuclear exosome (RNase complex) IBA
 cellular_componentGO:0000177 cytoplasmic exosome (RNase complex) IBA
 cellular_componentGO:0000178 exosome (RNase complex) IEA
 molecular_functionGO:0017091 AU-rich element binding IBA


Pathways (from Reactome)
Pathway description
mRNA decay by 3 to 5 exoribonuclease
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
KSRP (KHSRP) binds and destabilizes mRNA
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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