ENSDARG00000006514


Danio rerio

Features
Gene ID: ENSDARG00000006514
  
Biological name :her6
  
Synonyms : hairy-related 6 / her6
  
Possible biological names infered from orthology : HES1 / hes family bHLH transcription factor 1 / P35428 / Q14469 / Transcription factor HES-1
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 36551083
Gene end: 36552844
  
Corresponding Affymetrix probe sets: Dr.431.1.S1_at (Zebrafish Array)   NM_131079_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000018393
NCBI entrez gene - 30288     See in Manteia.
RefSeq - NM_131079
RefSeq Peptide - NP_571154
swissprot - Q6PBX3
ZFIN ID - ZDB-GENE-980526-144
Ensembl - ENSDARG00000006514
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HES1ENSG00000114315Homo sapiens
 Hes1ENSMUSG00000022528Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
her9 / hairy-related 9 / HES4* / Q9HCC6* / hes family bHLH transcription factor 4*ENSDARG0000005643864
her8a / hairy-related 8aENSDARG0000001636325
hes2.2 / hes family bHLH transcription factor 2, tandem duplicate 2 / HES2* / O54792* / Q9Y543* / Transcription factor HES-2 * / hes family bHLH transcription factor 2*ENSDARG0000006816823
her8.2 / hairy-related 8.2ENSDARG0000006967522
her13 / hairy-related 13 / HES6* / Q9JHE6* / Q96HZ4* / Transcription cofactor HES-6 * / hes family bHLH transcription factor 6*ENSDARG0000000709720
hes2.1 / hes family bHLH transcription factor 2, tandem duplicate 1 / HES2* / O54792* / Q9Y543* / Transcription factor HES-2 * / hes family bHLH transcription factor 2*ENSDARG0000007489720
hes6 / hes family bHLH transcription factor 6ENSDARG0000001933520


Protein motifs (from Interpro)
Interpro ID Name
 IPR003650  Orange domain
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001757 somite specification IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007219 Notch signaling pathway IMP
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0021794 thalamus development IMP
 biological_processGO:0045664 regulation of neuron differentiation IMP
 biological_processGO:0050767 regulation of neurogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain cell proliferation in hindbrain ventricular zone increased occurrence , abnormal
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 ZFA:0000079 telencephalon telencephalon postero-dorsal region cellular quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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