ENSDARG00000006978


Danio rerio

Features
Gene ID: ENSDARG00000006978
  
Biological name :zak
  
Synonyms : sterile alpha motif and leucine zipper containing kinase AZK / zak
  
Possible biological names infered from orthology : MAP3K20 / mitogen-activated protein kinase kinase kinase 20 / Q9ESL4 / Q9NYL2
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 2896009
Gene end: 2945008
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000150033
Ensembl peptide - ENSDARP00000093598
NCBI entrez gene - 559247     See in Manteia.
RefSeq - NM_001327940
RefSeq Peptide - NP_001314869
swissprot - B0S4Y7
ZFIN ID - ZDB-GENE-070912-386
Ensembl - ENSDARG00000006978
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAP3K20ENSGALG00000035237Gallus gallus
 Q9NYL2ENSG00000091436Homo sapiens
 Q9ESL4ENSMUSG00000004085Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zak / sterile alpha motif and leucine zipper containing kinase AZK / Q9ESL4* / Q9NYL2* / MAP3K20* / mitogen-activated protein kinase kinase kinase 20*ENSDARG0000004461534
map3k21 / mitogen-activated protein kinase kinase kinase 21 / Q5TCX8* / Q8VDG6*ENSDARG0000007947323
map3k10 / mitogen-activated protein kinase kinase kinase 10 / Q02779* / Q66L42*ENSDARG0000005567222
map3k12 / mitogen-activated protein kinase kinase kinase 12 / Q12852* / Q60700* / Mus musculus mitogen-activated protein kinase kinase kinase 12 (Map3k12), transcript variant 3, mRNA.*ENSDARG0000010365118
map3k9 / mitogen-activated protein kinase kinase kinase 9 / P80192* / Q3U1V8*ENSDARG0000001349118
MAP3K13 / si:ch211-45c16.2 / O43283* / Q1HKZ5* / mitogen-activated protein kinase kinase kinase 13*ENSDARG0000000949318
MAP3K11 / si:cabz01078036.1 / Q16584* / mitogen-activated protein kinase kinase kinase 11*ENSDARG0000009152117
map3k7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*ENSDARG0000002046914
tnni3k / TNNI3 interacting kinase / Q59H18* / Q5GIG6* / FPGT-TNNI3K* / FPGT-TNNI3K readthrough*ENSDARG0000008693313
ilk / integrin-linked kinase / O55222* / Q13418* / Integrin-linked protein kinase *ENSDARG000000569649
mos / v-mos Moloney murine sarcoma viral oncogene homolog / P00540* / MOS proto-oncogene, serine/threonine kinase*ENSDARG000000697449


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001660  Sterile alpha motif domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR032938  Mitogen-activated protein kinase kinase kinase MLT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007257 activation of JUN kinase activity IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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