ENSDARG00000103651


Danio rerio

Features
Gene ID: ENSDARG00000103651
  
Biological name :map3k12
  
Synonyms : map3k12 / mitogen-activated protein kinase kinase kinase 12
  
Possible biological names infered from orthology : Mus musculus mitogen-activated protein kinase kinase kinase 12 (Map3k12), transcript variant 3, mRNA. / Q12852 / Q60700
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 219124
Gene end: 235602
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000130149
NCBI entrez gene - 404626     See in Manteia.
RefSeq - NM_207094
RefSeq Peptide - NP_996977
swissprot - Q6NYW1
ZFIN ID - ZDB-GENE-040426-2436
Ensembl - ENSDARG00000103651
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000031572Gallus gallus
 Q12852ENSG00000139625Homo sapiens
 Q60700ENSMUSG00000023050Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAP3K13 / si:ch211-45c16.2 / O43283* / Q1HKZ5* / mitogen-activated protein kinase kinase kinase 13*ENSDARG0000000949356
map3k10 / mitogen-activated protein kinase kinase kinase 10 / Q02779* / Q66L42*ENSDARG0000005567223
map3k21 / mitogen-activated protein kinase kinase kinase 21 / Q5TCX8* / Q8VDG6*ENSDARG0000007947323
map3k9 / mitogen-activated protein kinase kinase kinase 9 / P80192* / Q3U1V8*ENSDARG0000001349119
MAP3K11 / si:cabz01078036.1 / Q16584* / mitogen-activated protein kinase kinase kinase 11*ENSDARG0000009152118
zak / sterile alpha motif and leucine zipper containing kinase AZK / Q9ESL4* / Q9NYL2* / MAP3K20* / mitogen-activated protein kinase kinase kinase 20*ENSDARG0000000697817
zak / sterile alpha motif and leucine zipper containing kinase AZK / Q9ESL4* / Q9NYL2* / MAP3K20* / mitogen-activated protein kinase kinase kinase 20*ENSDARG0000004461515
tnni3k / TNNI3 interacting kinase / Q59H18* / Q5GIG6* / FPGT-TNNI3K* / FPGT-TNNI3K readthrough*ENSDARG0000008693314
map3k7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*ENSDARG0000002046913
ilk / integrin-linked kinase / O55222* / Q13418* / Integrin-linked protein kinase *ENSDARG000000569649
mos / v-mos Moloney murine sarcoma viral oncogene homolog / P00540* / MOS proto-oncogene, serine/threonine kinase*ENSDARG000000697449


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017419  Mitogen-activated protein kinase kinase kinase 12/13
 IPR027257  Mitogen-activated protein kinase kinase kinase 12


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IBA
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007254 JNK cascade IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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