ENSDARG00000044615


Danio rerio

Features
Gene ID: ENSDARG00000044615
  
Biological name :zak
  
Synonyms : sterile alpha motif and leucine zipper containing kinase AZK / zak
  
Possible biological names infered from orthology : MAP3K20 / mitogen-activated protein kinase kinase kinase 20 / Q9ESL4 / Q9NYL2
  
Species: Danio rerio
  
Chr. number: 6
Strand: 1
Band:
Gene start: 6924637
Gene end: 6967588
  
Corresponding Affymetrix probe sets: DrAffx.1.40.S1_at (Zebrafish Array)   NM_212842_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000125869
Ensembl peptide - ENSDARP00000065550
NCBI entrez gene - 405768     See in Manteia.
RefSeq - NM_212842
RefSeq Peptide - NP_998007
swissprot - I3ISI6
swissprot - F1QGE4
ZFIN ID - ZDB-GENE-070912-386
Ensembl - ENSDARG00000044615
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAP3K20ENSGALG00000035237Gallus gallus
 Q9NYL2ENSG00000091436Homo sapiens
 Q9ESL4ENSMUSG00000004085Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
zak / sterile alpha motif and leucine zipper containing kinase AZK / Q9ESL4* / Q9NYL2* / MAP3K20* / mitogen-activated protein kinase kinase kinase 20*ENSDARG0000000697873
map3k21 / mitogen-activated protein kinase kinase kinase 21 / Q5TCX8* / Q8VDG6*ENSDARG0000007947338
map3k10 / mitogen-activated protein kinase kinase kinase 10 / Q02779* / Q66L42*ENSDARG0000005567236
map3k9 / mitogen-activated protein kinase kinase kinase 9 / P80192* / Q3U1V8*ENSDARG0000001349136
MAP3K13 / si:ch211-45c16.2 / O43283* / Q1HKZ5* / mitogen-activated protein kinase kinase kinase 13*ENSDARG0000000949334
map3k12 / mitogen-activated protein kinase kinase kinase 12 / Q12852* / Q60700* / Mus musculus mitogen-activated protein kinase kinase kinase 12 (Map3k12), transcript variant 3, mRNA.*ENSDARG0000010365134
MAP3K11 / si:cabz01078036.1 / Q16584* / mitogen-activated protein kinase kinase kinase 11*ENSDARG0000009152132
tnni3k / TNNI3 interacting kinase / Q59H18* / Q5GIG6* / FPGT-TNNI3K* / FPGT-TNNI3K readthrough*ENSDARG0000008693328
map3k7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*ENSDARG0000002046926
mos / v-mos Moloney murine sarcoma viral oncogene homolog / P00540* / MOS proto-oncogene, serine/threonine kinase*ENSDARG0000006974420
ilk / integrin-linked kinase / O55222* / Q13418* / Integrin-linked protein kinase *ENSDARG0000005696419


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR032938  Mitogen-activated protein kinase kinase kinase MLT


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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