ENSDARG00000009493


Danio rerio

Features
Gene ID: ENSDARG00000009493
  
Biological name :MAP3K13
  
Synonyms : MAP3K13 / si:ch211-45c16.2
  
Possible biological names infered from orthology : mitogen-activated protein kinase kinase kinase 13 / O43283 / Q1HKZ5
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 52694971
Gene end: 52814314
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000009159
Ensembl peptide - ENSDARP00000120489
NCBI entrez gene - 568412     See in Manteia.
swissprot - E7FH13
ZFIN ID - ZDB-GENE-081105-15
Ensembl - ENSDARG00000009493
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAP3K13ENSGALG00000006655Gallus gallus
 O43283ENSG00000073803Homo sapiens
 Q1HKZ5ENSMUSG00000033618Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
map3k12 / mitogen-activated protein kinase kinase kinase 12 / Q12852* / Q60700* / Mus musculus mitogen-activated protein kinase kinase kinase 12 (Map3k12), transcript variant 3, mRNA.*ENSDARG0000010365149
map3k21 / mitogen-activated protein kinase kinase kinase 21 / Q5TCX8* / Q8VDG6*ENSDARG0000007947321
map3k10 / mitogen-activated protein kinase kinase kinase 10 / Q02779* / Q66L42*ENSDARG0000005567221
map3k9 / mitogen-activated protein kinase kinase kinase 9 / P80192* / Q3U1V8*ENSDARG0000001349116
MAP3K11 / si:cabz01078036.1 / Q16584* / mitogen-activated protein kinase kinase kinase 11*ENSDARG0000009152116
zak / sterile alpha motif and leucine zipper containing kinase AZK / Q9ESL4* / Q9NYL2* / MAP3K20* / mitogen-activated protein kinase kinase kinase 20*ENSDARG0000000697814
zak / sterile alpha motif and leucine zipper containing kinase AZK / Q9ESL4* / Q9NYL2* / MAP3K20* / mitogen-activated protein kinase kinase kinase 20*ENSDARG0000004461513
tnni3k / TNNI3 interacting kinase / Q59H18* / Q5GIG6* / FPGT-TNNI3K* / FPGT-TNNI3K readthrough*ENSDARG0000008693312
map3k7 / mitogen-activated protein kinase kinase kinase 7 / O43318* / Q62073*ENSDARG0000002046911
ilk / integrin-linked kinase / O55222* / Q13418* / Integrin-linked protein kinase *ENSDARG000000569648
mos / v-mos Moloney murine sarcoma viral oncogene homolog / P00540* / MOS proto-oncogene, serine/threonine kinase*ENSDARG000000697448


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017419  Mitogen-activated protein kinase kinase kinase 12/13
 IPR027258  Mitogen-activated protein kinase kinase kinase 13


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007254 JNK cascade IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0008385 IkappaB kinase complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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