ENSMUSG00000033618


Mus musculus

Features
Gene ID: ENSMUSG00000033618
  
Biological name :Map3k13
  
Synonyms : Map3k13 / Mitogen-activated protein kinase kinase kinase 13 / Q1HKZ5
  
Possible biological names infered from orthology : O43283
  
Species: Mus musculus
  
Chr. number: 16
Strand: 1
Band: B1
Gene start: 21891969
Gene end: 21931877
  
Corresponding Affymetrix probe sets: 10434629 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000047388
NCBI entrez gene - 71751     See in Manteia.
MGI - MGI:2444243
RefSeq - XM_011246016
RefSeq - NM_172821
RefSeq - XM_006522584
RefSeq - XM_011246015
RefSeq - XM_006522582
RefSeq - XM_006522583
RefSeq Peptide - NP_766409
swissprot - Q1HKZ5
Ensembl - ENSMUSG00000033618
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAP3K13ENSDARG00000009493Danio rerio
 MAP3K13ENSGALG00000006655Gallus gallus
 O43283ENSG00000073803Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q60700 / Map3k12 / Mus musculus mitogen-activated protein kinase kinase kinase 12 (Map3k12), transcript variant 3, mRNA. / Q12852* / mitogen-activated protein kinase kinase kinase 12*ENSMUSG0000002305050
Q66L42 / Map3k10 / Mitogen-activated protein kinase kinase kinase 10 / Q02779*ENSMUSG0000004039024
Map3k9 / Q3U1V8 / Mitogen-activated protein kinase kinase kinase 9 / P80192*ENSMUSG0000004272424
Q8VDG6 / Map3k21 / Mitogen-activated protein kinase kinase kinase 21 / Q5TCX8*ENSMUSG0000003185323
Q80XI6 / Map3k11 / Mitogen-activated protein kinase kinase kinase 11 / Q16584*ENSMUSG0000000405421
Q9ESL4 / Map3k20 / Mitogen-activated protein kinase kinase kinase 20 / Q9NYL2*ENSMUSG0000000408516
Q5GIG6 / Tnni3k / TNNI3 interacting kinase / Q59H18* / FPGT-TNNI3K* / FPGT-TNNI3K readthrough*ENSMUSG0000004008613
Map3k7 / Q62073 / Mitogen-activated protein kinase kinase kinase 7 / O43318*ENSMUSG0000002828413
Ilk / O55222 / Integrin-linked protein kinase / Q13418* / integrin linked kinase*ENSMUSG000000308909
Mos / MOS proto-oncogene, serine/threonine kinase / P00540*ENSMUSG000000783658


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017419  Mitogen-activated protein kinase kinase kinase 12/13
 IPR027258  Mitogen-activated protein kinase kinase kinase 13


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0007254 JNK cascade IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0008385 IkappaB kinase complex IEA
 cellular_componentGO:0016020 membrane ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0004709 MAP kinase kinase kinase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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