ENSMUSG00000078365


Mus musculus

Features
Gene ID: ENSMUSG00000078365
  
Biological name :Mos
  
Synonyms : Mos / MOS proto-oncogene, serine/threonine kinase
  
Possible biological names infered from orthology : P00540
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A1
Gene start: 3870657
Gene end: 3872105
  
Corresponding Affymetrix probe sets: 10511330 (MoGene1.0st)   1450775_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000100789
NCBI entrez gene - 17451     See in Manteia.
MGI - MGI:97052
RefSeq - NM_020021
RefSeq Peptide - NP_064405
swissprot - F6UHW1
Ensembl - ENSMUSG00000078365
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mosENSDARG00000069744Danio rerio
 MOSENSGALG00000042082Gallus gallus
 MOSENSG00000172680Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8VDG6 / Map3k21 / Mitogen-activated protein kinase kinase kinase 21 / Q5TCX8*ENSMUSG0000003185327
Map3k9 / Q3U1V8 / Mitogen-activated protein kinase kinase kinase 9 / P80192*ENSMUSG0000004272424
Q60700 / Map3k12 / Mus musculus mitogen-activated protein kinase kinase kinase 12 (Map3k12), transcript variant 3, mRNA. / Q12852* / mitogen-activated protein kinase kinase kinase 12*ENSMUSG0000002305024
Q66L42 / Map3k10 / Mitogen-activated protein kinase kinase kinase 10 / Q02779*ENSMUSG0000004039024
Q80XI6 / Map3k11 / Mitogen-activated protein kinase kinase kinase 11 / Q16584*ENSMUSG0000000405423
Map3k7 / Q62073 / Mitogen-activated protein kinase kinase kinase 7 / O43318*ENSMUSG0000002828422
Q5GIG6 / Tnni3k / TNNI3 interacting kinase / Q59H18* / FPGT-TNNI3K* / FPGT-TNNI3K readthrough*ENSMUSG0000004008622
Q1HKZ5 / Map3k13 / Mitogen-activated protein kinase kinase kinase 13 / O43283*ENSMUSG0000003361822
Q9ESL4 / Map3k20 / Mitogen-activated protein kinase kinase kinase 20 / Q9NYL2*ENSMUSG0000000408521
Ilk / O55222 / Integrin-linked protein kinase / Q13418* / integrin linked kinase*ENSMUSG0000003089016


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Mostm1Sia/Mostm1Sia
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Mostm1Gvw/Mostm1Gvw
Genetic Background: involves: 129S1/Sv

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Mostm1Sia/Mostm1Sia
Genetic Background: involves: C57BL/6 * CBA

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Mostm1Sia/Mostm1Sia
Genetic Background: involves: C57BL/6 * CBA

 MP:0002016 ovarian cysts "cystic ovary; usually refers to a benign growth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]
Show

Allelic Composition: Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0002627 teratoma "neoplasms composed of multiple tissue types; includes types not found in tissue in which lesion arises" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Mostm1Sia/Mostm1Sia
Genetic Background: involves: C57BL/6 * CBA

 MP:0005168 abnormal female meiosis "malfunction in the process of nuclear division that results in ova with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Mostm1Sia/Mostm1Sia
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Mostm1Gvw/Mostm1Gvw
Genetic Background: involves: 129S1/Sv

 MP:0009443 parthenogenesis "development of an egg into a diploid embryo without being fertilized" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mostm1Gvw/Mostm1Gvw
Genetic Background: involves: 129S1/Sv

 MP:0009761 abnormal meiotic spindle "an anomaly in the formation of the ellipsoidal (bipolar) collection of fibers visible during nuclear division and cytokinesis responsible for accurate segregation of chromosomes during meiosis" [ISBN:8185198691 "Rieger R et al Eds Glossary of Genetics Classical and Molecular"]
Show

Allelic Composition: Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

Allelic Composition: Mostm1Gvw/Mostm1Gvw
Genetic Background: involves: 129S1/Sv

 MP:0012736 abnormal polar body morphology "any structural anomaly of one of the small cells that are produced during the development of an oocyte and ultimately degenerate; a polar body contains one of the nuclei derived from the first or second meiotic division but little or no cytoplasm" [MGI:anna]
Show

Allelic Composition: Alx4tm1Rwi/Alx4tm1Rwi
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J

 MP:0012737 abnormal primary polar body morphology "any structural anomaly of the small cell formed by the first meiotic division of oocytes" [MGI:anna]
Show

Allelic Composition: Mostm1Gvw/Mostm1Gvw
Genetic Background: involves: 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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