ENSG00000172680


Homo sapiens

Features
Gene ID: ENSG00000172680
  
Biological name :MOS
  
Synonyms : MOS / MOS proto-oncogene, serine/threonine kinase / P00540
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q12.1
Gene start: 56112942
Gene end: 56113982
  
Corresponding Affymetrix probe sets: 221367_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000310722
NCBI entrez gene - 4342     See in Manteia.
OMIM - 190060
RefSeq - NM_005372
RefSeq Peptide - NP_005363
swissprot - P00540
Ensembl - ENSG00000172680
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mosENSDARG00000069744Danio rerio
 MOSENSGALG00000042082Gallus gallus
 MosENSMUSG00000078365Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5TCX8 / MAP3K21 / mitogen-activated protein kinase kinase kinase 21ENSG0000014367426
Q12852 / MAP3K12 / mitogen-activated protein kinase kinase kinase 12ENSG0000013962525
MAP3K9 / P80192 / mitogen-activated protein kinase kinase kinase 9ENSG0000000643225
Q02779 / MAP3K10 / mitogen-activated protein kinase kinase kinase 10ENSG0000013075824
O43283 / MAP3K13 / mitogen-activated protein kinase kinase kinase 13ENSG0000007380324
Q16584 / MAP3K11 / mitogen-activated protein kinase kinase kinase 11ENSG0000017332723
Q59H18 / TNNI3K / TNNI3 interacting kinaseENSG0000011678321
FPGT-TNNI3K / FPGT-TNNI3K readthroughENSG0000025903021
MAP3K7 / O43318 / mitogen-activated protein kinase kinase kinase 7ENSG0000013534121
Q9NYL2 / MAP3K20 / mitogen-activated protein kinase kinase kinase 20ENSG0000009143620
ILK / Q13418 / integrin linked kinaseENSG0000016633316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000186 activation of MAPKK activity ISS
 biological_processGO:0000187 activation of MAPK activity ISS
 biological_processGO:0000212 meiotic spindle organization ISS
 biological_processGO:0006325 chromatin organization ISS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0046777 protein autophosphorylation ISS
 biological_processGO:0051296 establishment of meiotic spindle orientation ISS
 biological_processGO:1902103 negative regulation of metaphase/anaphase transition of meiotic cell cycle IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity ISS
 molecular_functionGO:0004871 obsolete signal transducer activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr