ENSMUSG00000042724


Mus musculus

Features
Gene ID: ENSMUSG00000042724
  
Biological name :Map3k9
  
Synonyms : Map3k9 / Mitogen-activated protein kinase kinase kinase 9 / Q3U1V8
  
Possible biological names infered from orthology : P80192
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: D1
Gene start: 81721010
Gene end: 81781175
  
Corresponding Affymetrix probe sets: 10401343 (MoGene1.0st)   1432981_at (Mouse Genome 430 2.0 Array)   1455684_at (Mouse Genome 430 2.0 Array)   1458922_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041819
Ensembl peptide - ENSMUSP00000152201
NCBI entrez gene - 338372     See in Manteia.
MGI - MGI:2449952
RefSeq - XM_017315122
RefSeq - NM_001174107
RefSeq - NM_177395
RefSeq - XM_006516036
RefSeq - XM_006516037
RefSeq Peptide - NP_001167578
RefSeq Peptide - NP_796369
swissprot - Q3U1V8
swissprot - A0A1Y7VKX4
Ensembl - ENSMUSG00000042724
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 map3k9ENSDARG00000013491Danio rerio
 MAP3K9ENSGALG00000037326Gallus gallus
 MAP3K9ENSG00000006432Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q66L42 / Map3k10 / Mitogen-activated protein kinase kinase kinase 10 / Q02779*ENSMUSG0000004039053
Q8VDG6 / Map3k21 / Mitogen-activated protein kinase kinase kinase 21 / Q5TCX8*ENSMUSG0000003185344
Q80XI6 / Map3k11 / Mitogen-activated protein kinase kinase kinase 11 / Q16584*ENSMUSG0000000405439
Q1HKZ5 / Map3k13 / Mitogen-activated protein kinase kinase kinase 13 / O43283*ENSMUSG0000003361822
Q60700 / Map3k12 / Mus musculus mitogen-activated protein kinase kinase kinase 12 (Map3k12), transcript variant 3, mRNA. / Q12852* / mitogen-activated protein kinase kinase kinase 12*ENSMUSG0000002305020
Q9ESL4 / Map3k20 / Mitogen-activated protein kinase kinase kinase 20 / Q9NYL2*ENSMUSG0000000408519
Map3k7 / Q62073 / Mitogen-activated protein kinase kinase kinase 7 / O43318*ENSMUSG0000002828415
Q5GIG6 / Tnni3k / TNNI3 interacting kinase / Q59H18* / FPGT-TNNI3K* / FPGT-TNNI3K readthrough*ENSMUSG0000004008614
Ilk / O55222 / Integrin-linked protein kinase / Q13418* / integrin linked kinase*ENSMUSG000000308909
Mos / MOS proto-oncogene, serine/threonine kinase / P00540*ENSMUSG000000783658


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001452  SH3 domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR016231  Mitogen-activated protein (MAP) kinase kinase kinase, MLK1-4
 IPR017441  Protein kinase, ATP binding site
 IPR035779  MLK1-3, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IEA
 biological_processGO:0000186 activation of MAPKK activity IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007256 activation of JNKK activity IEA
 biological_processGO:0007257 activation of JUN kinase activity IBA
 biological_processGO:0008219 cell death IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004706 JUN kinase kinase kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Sharpincpdm/Sharpincpdm
Genetic Background: involves: C57BL/KaLawRij * FVB/NJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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