ENSDARG00000008384


Danio rerio

Features
Gene ID: ENSDARG00000008384
  
Biological name :hdac6
  
Synonyms : hdac6 / histone deacetylase 6
  
Possible biological names infered from orthology : Q9UBN7 / Q9Z2V5
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 7393435
Gene end: 7444390
  
Corresponding Affymetrix probe sets: Dr.4465.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124512
Ensembl peptide - ENSDARP00000153983
Ensembl peptide - ENSDARP00000124246
NCBI entrez gene - 565482     See in Manteia.
RefSeq - XM_009303751
RefSeq - XM_009303752
swissprot - F8W336
swissprot - F8W4B7
ZFIN ID - ZDB-GENE-030131-3232
Ensembl - ENSDARG00000008384
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HDAC6ENSG00000094631Homo sapiens
 Hdac6ENSMUSG00000031161Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hdac10 / histone deacetylase 10 / Q6P3E7* / Q969S8*ENSDARG0000008645823
hdac4 / histone deacetylase 4 / P56524* / Q6NZM9*ENSDARG0000009834921
hdac5 / histone deacetylase 5 / Q9UQL6* / histone deacetylase 5 isoform 4 *ENSDARG0000007513921
hdac7b / histone deacetylase 7b / HDAC7* / Q8WUI4* / Q8C2B3* / histone deacetylase 7*ENSDARG0000007385018
CABZ01074076.1 / HDAC7* / Q8C2B3* / Q8WUI4* / histone deacetylase 7*ENSDARG0000010517915
hdac9b / histone deacetylase 9b / HDAC9* / Q9UKV0* / histone deacetylase 9*ENSDARG000000566425


Protein motifs (from Interpro)
Interpro ID Name
 IPR000286  Histone deacetylase family
 IPR001607  Zinc finger, UBP-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR023801  Histone deacetylase domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IMP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006476 protein deacetylation IGI
 biological_processGO:0016575 histone deacetylation IEA
 biological_processGO:0060216 definitive hemopoiesis IMP
 biological_processGO:0070932 histone H3 deacetylation IEA
 biological_processGO:0090042 tubulin deacetylation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0004407 histone deacetylase activity IEA
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030955 potassium ion binding IDA
 molecular_functionGO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
 molecular_functionGO:0033558 protein deacetylase activity IDA
 molecular_functionGO:0042903 tubulin deacetylase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HSF1 activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020008 vcp / Q7ZU99 / valosin containing protein / P55072* / Q01853*  / complex






 

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