ENSDARG00000013150


Danio rerio

Features
Gene ID: ENSDARG00000013150
  
Biological name :dhx16
  
Synonyms : DEAH (Asp-Glu-Ala-His) box polypeptide 16 / dhx16
  
Possible biological names infered from orthology : DEAH-box helicase 16 / O60231
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 34899645
Gene end: 34934784
  
Corresponding Affymetrix probe sets: Dr.6660.1.S1_at (Zebrafish Array)   NM_200024_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000002154
Ensembl peptide - ENSDARP00000152608
Ensembl peptide - ENSDARP00000154340
NCBI entrez gene - 336645     See in Manteia.
RefSeq - NM_200024
RefSeq Peptide - NP_956318
swissprot - F1QU72
ZFIN ID - ZDB-GENE-030131-8589
Ensembl - ENSDARG00000013150
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DHX16ENSG00000204560Homo sapiens
 Dhx16ENSMUSG00000024422Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dhx8 / DEAH (Asp-Glu-Ala-His) box polypeptide 8 / Q14562* / A2A4P0* / DEAH-box helicase 8* / ATP-dependent RNA helicase DHX8 *ENSDARG0000005470742
dhx38 / DEAH (Asp-Glu-Ala-His) box polypeptide 38 / Q92620* / DEAH-box helicase 38*ENSDARG0000010001337
dhx15 / DEAH (Asp-Glu-Ala-His) box helicase 15 / O35286* / O43143* / DEAH-box helicase 15* / Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 *ENSDARG0000001539234
dhx33 / DEAH (Asp-Glu-Ala-His) box polypeptide 33 / Q80VY9* / Q9H6R0* / DEAH-box helicase 33* / Putative ATP-dependent RNA helicase DHX33 *ENSDARG0000005178528
dhx40 / DEAH (Asp-Glu-Ala-His) box polypeptide 40 / Q6PE54* / Q8IX18* / DEAH-box helicase 40* / Probable ATP-dependent RNA helicase DHX40 *ENSDARG0000004158627
dhx34 / DEAH (Asp-Glu-Ala-His) box polypeptide 34 / Q14147* / DExH-box helicase 34*ENSDARG0000006116823
DHX35 / zgc:158828 / Q9H5Z1* / DEAH-box helicase 35* / probable ATP-dependent RNA helicase DHX35 isoform b *ENSDARG0000006341921


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR002464  DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
 IPR007502  Helicase-associated domain
 IPR011545  DEAD/DEAH box helicase domain
 IPR011709  Domain of unknown function DUF1605
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0035987 endodermal cell differentiation IMP
 cellular_componentGO:0005681 spliceosomal complex IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain quality , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary condensed , abnormal
midbrain hindbrain boundary quality , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
yolk quality , abnormal
Show

 ZFA:0000106 extension extension decreased thickness , abnormal
Show

 ZFA:0000109 forebrain forebrain pointed , abnormal
forebrain quality , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism anterior-posterior axis decreased length , abnormal
whole organism anterior-posterior axis bent , abnormal
whole organism shape , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
head necrotic , abnormal
Show

 ZFA:0001115 trunk trunk decreased thickness , abnormal
Show

 ZFA:0001176 blastoderm blastoderm increased thickness , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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